20 articles
A new framework proposes organ-specific biological clocks using multi-omics data to better predict disease onset and aging trajectories.
Specific mutational signatures accumulate linearly with age in normal tissues, offering a new window into why cancer risk rises exponentially as we get older.
Scientists propose space environments as unique models for studying accelerated aging mechanisms and potential interventions.
A new Cell Metabolism review from NIH identifies how ECM stiffening, poor blood flow, and mitochondrial failure lock tissues into accelerating decline.
Researchers outline innovative approaches to speed up drug development for age-related diseases and longevity interventions.
A landmark review maps the structural, genetic, and molecular changes that erode lung function with age — and why reversing them matters.
A new review maps the bidirectional crosstalk between gut microbiota and cellular senescence driving multi-organ degeneration.
A new review reframes magnesium as a master regulator of mitochondrial energy, metabolic disease, and biological aging.
New research reveals how people over 100 maintain youthful immune systems despite chronic inflammation, offering insights for healthy aging.
A new framework redefines age-related insulin resistance as a systemic collapse of metabolic resilience spanning muscle, fat, brain, and more.
A landmark review reveals how sustained glucocorticoid exposure drives aging biology — and what can be done about it.
Aging disrupts gut microbiota and mTOR signaling, crippling vaccine responses — but targeted interventions may reverse this.
Age-related shifts in intestinal T cell populations may silently erode gut barrier function, accelerating the chronic inflammation that drives aging diseases.
A landmark review maps the three pillars of modern lineage tracing and how they're reshaping our understanding of cell fate decisions.
Expert reviews compare leading senolytic and NAD+ supplement brands on ingredients, evidence quality, and value.
Six leading CGM platforms compared on accuracy, evidence quality, and longevity claims — most fall short of the hype.
A scoping review exposes deep conceptual gaps in how physical resilience is defined and measured across aging and rehabilitation science.
Continuous glucose monitors are popular in biohacking circles, but direct evidence linking CGM use to extended lifespan remains thin.
Top longevity doctors endorse CGMs for healthy adults, but evidence is mixed. Here's what the 2026 device reviews reveal.
Expert reviews of top CGM platforms reveal genuine metabolic insights — but no proof they extend lifespan in healthy adults.
