20 articles
A major review outlines how targeted hematologic therapies are transforming outcomes in MGRS, a rare but serious cause of kidney injury.
New research reveals mortality from this rare immune disorder varies by time, potentially improving treatment strategies.
Groundbreaking study reveals how B cells acquire mutations in checkpoint genes to bypass immune tolerance in autoimmune thyroid disease.
New research reveals how aggressive T cell lymphomas exploit the same pathways that normally activate healthy immune responses.
Scientists discover how immune cells work together in unexpected ways, opening new paths for cancer therapy and transplant success.
A randomized trial shows prophylactic obinutuzumab dramatically reduces steroid-requiring cGVHD after bone marrow transplant.
Scientists use human blood vessel organoids to decode the progression of systemic sclerosis, revealing new therapeutic targets.
HSCT therapy achieves drug-free remission in patients with treatment-resistant autoimmune conditions like lupus and rheumatoid arthritis.
New research reveals how the immune system's own antibodies trigger diversification, creating broader protection against pathogens.
New research reveals how three types of helper T cells work together to trigger harmful autoimmune responses in tissues.
A major review in Nature Medicine explores how CAR cell therapies may achieve deep immune 'reset' in autoimmune diseases by depleting pathogenic B cells.
A randomized phase 2 trial finds CM313 achieves 83% response rate vs 20% placebo in treatment-resistant immune thrombocytopenia.
Researchers identify OGFRL1 gene deficiency as a novel cause of chronic bone disease, with promising treatment response to TNF inhibitors.
A completed Phase 3 trial tests placental MSC secretome injections against placebo in 60 GvHD patients at an Iranian hospital.
A new in vitro study shows Thymosin ฮฑ1 triggers dendritic cells to release IL-15, boosting CD8+ T cell killing and reducing HIV reservoir size.
Scientists identify key mechanism that determines why some immune thrombocytopenia patients maintain remission after stopping treatment.
Scientists discover transitional dendritic cells that regulate immune responses, offering new targets for cancer therapy.
Scientists developed a breakthrough method to analyze thousands of immune cells simultaneously, revealing new insights into autoimmune diseases.
Researchers modified red blood cells to teach the immune system tolerance, potentially ending need for harsh immunosuppressive drugs.
Enhanced immune cells engineered with cytokines could overcome cancer's defenses and extend treatment options beyond blood cancers.
