New Anemia Drug GSK1278863 Tested as Replacement for EPO in Kidney Disease Patients
A Phase IIa trial explores whether the HIF-PHI drug daprodustat can safely replace EPO injections in hemodialysis patients with anemia.
20 articles
A Phase IIa trial explores whether the HIF-PHI drug daprodustat can safely replace EPO injections in hemodialysis patients with anemia.
Small pilot study explored whether platelets could serve as biomarkers for detecting mitochondrial problems linked to diabetes development.
Researchers mapped how anesthetics, nitric oxide, and other drugs alter hemoglobin's grip on oxygen โ with real implications for critical care.
A Danish case-control trial uses gold-standard metabolic testing to uncover how mtDNA mutations impair muscle glucose uptake and drive insulin resistance.
A completed Danish trial investigates how blocking IL-6 signaling with tocilizumab alters fat, glucose, and protein metabolism in humans.
French study reveals how aging influences metabolic responses to cancer, potentially explaining malnutrition patterns in elderly patients.
Major study shows lifestyle intervention effectively reverses prediabetes in both African American and Caucasian participants with family diabetes history.
Study reveals how lean people can still have obesity-like metabolism and whether calorie restriction helps reverse this dangerous condition.
Swiss researchers studied how mTOR protein in fat tissue affects metabolism and insulin function throughout the body.
Carmot Therapeutics tests CT-868, a novel dual incretin receptor agonist, for HbA1c reduction in overweight and obese adults with poorly controlled T2DM.
A completed Maastricht trial tests whether targeted protein and exercise can boost muscle protein synthesis before dialysis becomes necessary.
New study reveals how endurance exercise transforms fat-burning brown adipose tissue in just six weeks of training.
176-person study explored personalized responses to refined carbs, whole grains, and intermittent fasting for optimal glucose control.
Researchers test lipid, glucose, and mixed meal challenges to pinpoint optimal post-meal sample collection windows for future cardiovascular studies.
New research shows high-intensity interval training just once per week can improve obesity and fatty liver disease over a full year.
A completed OSU trial investigates whether short-term exercise training can restore impaired mitochondrial cleanup pathways in overweight and obese skeletal muscle.
Study reveals how newborn care disrupts mothers' circadian rhythms, potentially affecting long-term metabolic health and diabetes risk.
Duke study shows high-quality egg protein combined with calorie restriction improves metabolic outcomes in older adults with prediabetes.
12-week study tested whether eating just 25% of calories two days per week could help HIV patients lose weight and improve metabolism.
A completed trial investigates whether replenishing glutathione precursors can reverse metabolic dysfunction in elderly adults.