Blood Cell Mutations Linked to Higher Heart Inflammation Risk in Major US Study
New research reveals how age-related blood cell changes may increase pericarditis and myocarditis risk in healthy adults.
20 articles
New research reveals how age-related blood cell changes may increase pericarditis and myocarditis risk in healthy adults.
New research reveals potential cancer risks following advanced CAR T-cell immunotherapy treatments.
Scientists discover how damaged heart cells transform into new blood vessels, potentially revolutionizing heart failure treatment.
Researchers discovered specific cell markers that predict which leukemia patients will achieve lasting remission from CAR-T therapy.
Scientists discover how an unusual gene fusion in melanoma still drives cancer growth and responds to targeted treatment.
Researchers created the first comprehensive atlas of bone metastases, revealing new immune therapy combinations that could help patients.
Researchers propose targeting lymph node entry mechanisms to improve immune tolerance in cardiac transplant recipients, potentially reducing rejection.
Scientists identify a natural genetic variant that improves blood clotting factor VIII activity, offering insights for bleeding disorders.
New molecular analysis reveals cardiac sarcoidosis triggers self-targeting antibodies against a desmosome protein, explaining its overlap with arrhythmic heart disease.
A feedforward ANGPT-TIE2 signaling loop amplifies PIK3CA-driven venous malformations, pointing to TIE2 inhibition as a more effective therapy than mTOR blockade.
A newly identified molecular glitch in MAML1 phase separation disrupts Notch signaling and causes ventricular septal defects.
A completed registry study identified and genotyped HoFH patients with LDLR mutations, laying groundwork for targeted gene therapy.
Advanced spatial mapping shows vascular regions drive cardiac aging through inflammation and senescence accumulation.
A distinct immune remodeling process โ separate from classical immunosenescence โ predicts arterial stiffness with surprising accuracy.
New research reveals how genetics, age, and herpesvirus infections create unique immune profiles that affect disease severity.
Small trial tests safety of injecting patients' own cardiac stem cells to regrow dead heart tissue and restore function.
A comprehensive review reveals the complex genetic architecture of familial hypercholesterolaemia, where polygenic and Lp(a) mechanisms explain most 'mutation-negative' cases.
Scientists discover cancer-specific RNA molecules in blood that could revolutionize early detection and monitoring.
A single cardiovascular event creates inflammatory memory that drives chronic disease across multiple organs for years.
Researchers tested whether stem cells from healthy hearts could help repair damage in heart attack patients, offering hope for cardiac regeneration.