Results for "Clonal Hematopoiesis" in Heart Disease

20 articles

Blood Cell Mutations Linked to Higher Heart Inflammation Risk in Major US Study
Heart Health

Blood Cell Mutations Linked to Higher Heart Inflammation Risk in Major US Study

New research reveals how age-related blood cell changes may increase pericarditis and myocarditis risk in healthy adults.

Research Paper
Mar 28, 2026 0
CAR T-Cell Cancer Treatment Linked to Secondary Lymphoma Risk
Heart Health

CAR T-Cell Cancer Treatment Linked to Secondary Lymphoma Risk

New research reveals potential cancer risks following advanced CAR T-cell immunotherapy treatments.

Research Paper
Mar 29, 2026 0
Heart Failure Recovery Driven by Cells Converting to Blood Vessels
Heart Health

Heart Failure Recovery Driven by Cells Converting to Blood Vessels

Scientists discover how damaged heart cells transform into new blood vessels, potentially revolutionizing heart failure treatment.

Research Paper
Mar 28, 2026 1
Scientists Identify CAR-T Cell Markers That Predict Long-Term Cancer Remission
Heart Health

Scientists Identify CAR-T Cell Markers That Predict Long-Term Cancer Remission

Researchers discovered specific cell markers that predict which leukemia patients will achieve lasting remission from CAR-T therapy.

Research Paper
Mar 29, 2026 3
Rare Cancer Gene Fusion Responds to Targeted Therapy Despite Unusual Structure
Heart Health

Rare Cancer Gene Fusion Responds to Targeted Therapy Despite Unusual Structure

Scientists discover how an unusual gene fusion in melanoma still drives cancer growth and responds to targeted treatment.

Research Paper
Mar 28, 2026 1
Scientists Map Bone Cancer Spread to Unlock New Immunotherapy Targets
Heart Health

Scientists Map Bone Cancer Spread to Unlock New Immunotherapy Targets

Researchers created the first comprehensive atlas of bone metastases, revealing new immune therapy combinations that could help patients.

Research Paper
Mar 29, 2026 3
New Strategy Targets Lymph Node Pathways to Prevent Heart Transplant Rejection
Heart Health

New Strategy Targets Lymph Node Pathways to Prevent Heart Transplant Rejection

Researchers propose targeting lymph node entry mechanisms to improve immune tolerance in cardiac transplant recipients, potentially reducing rejection.

Research Paper
May 19, 2026 0
Rare Factor VIII Mutation Shows Enhanced Blood Clotting Function
Heart Health

Rare Factor VIII Mutation Shows Enhanced Blood Clotting Function

Scientists identify a natural genetic variant that improves blood clotting factor VIII activity, offering insights for bleeding disorders.

Research Paper
Mar 29, 2026 0
Cardiac Sarcoidosis Linked to Autoimmune Attack on Heart's Own Proteins
Heart Health

Cardiac Sarcoidosis Linked to Autoimmune Attack on Heart's Own Proteins

New molecular analysis reveals cardiac sarcoidosis triggers self-targeting antibodies against a desmosome protein, explaining its overlap with arrhythmic heart disease.

Research Paper
Jun 1, 2026 0
TIE2 Receptor Circuit Drives Venous Malformation Growth Beyond PI3K Mutations
Heart Health

TIE2 Receptor Circuit Drives Venous Malformation Growth Beyond PI3K Mutations

A feedforward ANGPT-TIE2 signaling loop amplifies PIK3CA-driven venous malformations, pointing to TIE2 inhibition as a more effective therapy than mTOR blockade.

Research Paper
May 22, 2026 0
Faulty Protein Condensates Drive Congenital Heart Defects via Notch Shutdown
Heart Health

Faulty Protein Condensates Drive Congenital Heart Defects via Notch Shutdown

A newly identified molecular glitch in MAML1 phase separation disrupts Notch signaling and causes ventricular septal defects.

Research Paper
Jun 6, 2026 0
REGENXBIO Hunts LDLR Mutations to Build a Gene Therapy Pipeline for Rare Cholesterol Disorder
Heart Health

REGENXBIO Hunts LDLR Mutations to Build a Gene Therapy Pipeline for Rare Cholesterol Disorder

A completed registry study identified and genotyped HoFH patients with LDLR mutations, laying groundwork for targeted gene therapy.

Clinical Trial
May 28, 2026 0
Heart's Blood Vessels Are Primary Aging Hotspots, Spatial Analysis Reveals
Heart Health

Heart's Blood Vessels Are Primary Aging Hotspots, Spatial Analysis Reveals

Advanced spatial mapping shows vascular regions drive cardiac aging through inflammation and senescence accumulation.

Research Paper
Mar 29, 2026 1
CD4+ T Cells Drive a New Form of Vascular Aging Linked to Arterial Stiffness
Heart Health

CD4+ T Cells Drive a New Form of Vascular Aging Linked to Arterial Stiffness

A distinct immune remodeling process โ€” separate from classical immunosenescence โ€” predicts arterial stiffness with surprising accuracy.

Research Paper
Jun 5, 2026 0
Your Genetics and Past Infections Shape How Well Your Immune System Fights Disease
Heart Health

Your Genetics and Past Infections Shape How Well Your Immune System Fights Disease

New research reveals how genetics, age, and herpesvirus infections create unique immune profiles that affect disease severity.

Research Paper
Mar 28, 2026 1
Cardiac Stem Cell Therapy Shows Promise for Regenerating Heart Muscle After Attack
Heart Health

Cardiac Stem Cell Therapy Shows Promise for Regenerating Heart Muscle After Attack

Small trial tests safety of injecting patients' own cardiac stem cells to regrow dead heart tissue and restore function.

Clinical Trial
Mar 28, 2026 4
Only 1 in 5 Suspected FH Patients Have a Detectable Gene Mutation
Heart Health

Only 1 in 5 Suspected FH Patients Have a Detectable Gene Mutation

A comprehensive review reveals the complex genetic architecture of familial hypercholesterolaemia, where polygenic and Lp(a) mechanisms explain most 'mutation-negative' cases.

Research Paper
Jun 8, 2026 0
Blood Test Detects Cancer Using Unique RNA Signatures Found in Tumor Cells
Heart Health

Blood Test Detects Cancer Using Unique RNA Signatures Found in Tumor Cells

Scientists discover cancer-specific RNA molecules in blood that could revolutionize early detection and monitoring.

Research Paper
Mar 29, 2026 3
How One Heart Attack or Stroke Programs Your Immune System for Lifelong Disease
Heart Health

How One Heart Attack or Stroke Programs Your Immune System for Lifelong Disease

A single cardiovascular event creates inflammatory memory that drives chronic disease across multiple organs for years.

Research Paper
Mar 29, 2026 1
Heart Stem Cell Trial Shows Promise for Regenerating Damaged Heart Muscle After Attack
Heart Health

Heart Stem Cell Trial Shows Promise for Regenerating Damaged Heart Muscle After Attack

Researchers tested whether stem cells from healthy hearts could help repair damage in heart attack patients, offering hope for cardiac regeneration.

Clinical Trial
Mar 28, 2026 1
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