Endogenous Aldehydes May Drive Blood Cell Mutations From Within Our Bodies
New research explores how naturally occurring aldehydes in our bodies might trigger clonal hematopoiesis, a blood disorder linked to aging.
20 articles
New research explores how naturally occurring aldehydes in our bodies might trigger clonal hematopoiesis, a blood disorder linked to aging.
New research reveals how thrombopoietin hormone establishes lifelong blood stem cell hierarchy in newborns.
New research reveals how endogenous formaldehyde causes stem cell damage, leading to clonal blood disorders throughout life.
A landmark effort to bank immune-compatible stem cells matched to the majority of the US population โ now terminated.
New research reveals how distinct brain stem cell types create neurons and support cells through unique developmental programs.
Harvard researchers identify a rare mesenchymal cell type that regenerates the thymus and boosts T cell immunity in aged animals.
NIDCR researchers compared stromal cells from bone marrow, skin, spleen, and fat to identify which best regenerates bone and supports blood formation.
Research reveals mechanisms behind the critical transition from fetal to adult hemoglobin, opening new treatment pathways.
Breakthrough stem cell platform creates scalable, genetically enhanced immune cells that could revolutionize cancer treatment.
Revolutionary delivery system uses red blood cells to program immune cells in the spleen to fight cancer tumors.
Scientists used patient-derived organoids to discover how breast cancer cells undergo epigenetic changes that enable metastasis.
Researchers developed 50 stem cell lines from HIV patients to understand genetic factors that determine disease progression.
Scientists converted fibroblasts into functional osteoblasts using small molecules, then formed transplantable spheroids that repair bone defects without scaffolding.
Scientists created modified stem cells that home to bone marrow, delivering targeted immune therapies while avoiding tumors entirely.
Kyoto researchers built the first fully in vitro system that guides stem cells through every stage of human thymus development, producing functional T cells.
Injured artery smooth muscle cells temporarily become stem-like progenitors, fueling the dangerous buildup that narrows blood vessels after cardiac procedures.
A landmark review maps the three pillars of modern lineage tracing and how they're reshaping our understanding of cell fate decisions.
Scientists engineer high-PS procoagulant platelets that outperform thrombin and commercial hemostatic agents, even in antiplatelet-treated patients.
Breakthrough chemical reprogramming method transforms ordinary blood cells into versatile stem cells without genetic modification.
Harvard's CellCartographer uses machine learning to identify optimal transcription factor combinations for rapid, high-efficiency cell reprogramming.