GLP-1 and PPARΞ³ Drugs Show Direct Brain Insulin-Signaling Effects
Stanford researchers find pioglitazone and liraglutide improve CNS insulin signaling, measured via neuron-derived vesicles in blood.
20 articles
Stanford researchers find pioglitazone and liraglutide improve CNS insulin signaling, measured via neuron-derived vesicles in blood.
Transdermal alcohol monitors paired with machine learning can now detect drinking events with over 90% accuracy β a leap beyond flawed self-reports.
New research reveals how glucose availability directs brain cell proliferation via a metabolic-epigenetic axis, with implications for MS and brain repair.
A landmark review proposes a paradigm shift in neurocritical care, moving from static ICP thresholds to dynamic intracranial monitoring of autoregulation, glymphatics, and compliance.
MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.
New study combines smartphone sensors, brain scans, and daily check-ins to predict suicide risk in vulnerable patients.
AI framework Reti-Pioneer screens for seven systemic diseases from a retinal photo, outperforming standard lab tests in speed and accuracy.
Emergency case study shows how brain imaging helps diagnose life-threatening metabolic crisis in alcohol-related emergency.
A new study warns that diabetes medications could confound Alzheimer's biomarker studies, distorting our understanding of the diabetes-dementia link.
A cohort of 18,000+ children and adults self-reported seizure durations, revealing patterns that could reshape clinical tracking and care.
A take-home brain-computer interface restored daily communication and control for a man with motor neuron disease, marking a milestone in neurotechnology.
Revolutionary Wave-CAIPI technology dramatically reduces brain scan time while maintaining accuracy for monitoring Alzheimer's treatments.
People with mild cognitive impairment recruit extra brain regions and show altered muscle control just to stay balanced while thinking.
A surprising new role for brain immune cells: microglia orchestrate glucose delivery to fuel memory-forming protein synthesis in active neurons.
A validated UPLC-MS/MS method analyzing 566 plasma samples reveals key patient factors that explain why standard antidepressant doses fail many people.
A global consortium reveals how tube type, delays, and storage temperature dramatically skew key Alzheimer's blood biomarker readings.
DNA methylation biomarkers from a simple blood test may track cognitive aging and neurological disease risk with unprecedented precision.
A 9-day intranasal insulin regimen restored working memory, recognition memory, and reduced neuroinflammation in mice engineered to mimic hippocampal aging.
First 7T MRI study reveals distinct brain chemistry differences between ME/CFS and long COVID patients despite similar fatigue symptoms.
A Mayo Clinic study reveals the Lumipulse p-tau217/AΞ²42 plasma ratio has variable accuracy in detecting Alzheimer's amyloid pathology.