Longevity & Aging
Senolytic Drug Combo Shows Promise for Alzheimer's Prevention in Pilot Study
Small trial tests whether dasatinib plus quercetin can improve brain blood flow and cognition in at-risk older adults.
Clinical Trial
Mar 28, 2026 1
Results for "Dasatinib + Quercetin"
20 articles
Brain Health
Dasatinib and Quercetin Reach the Brain in Early Alzheimer's Patients
A completed Phase 1/2 pilot trial tested whether the senolytic duo D+Q penetrates the brain in early Alzheimer's disease.
Clinical Trial
May 28, 2026 0
Longevity & Aging
Senolytic Drug Combo Shows Promise for Reversing Liver Fibrosis in NAFLD Patients
Clinical trial tests whether dasatinib plus quercetin can reduce liver scarring in fatty liver disease patients.
Clinical Trial
Mar 28, 2026 1
Cancer Research
HDAC Inhibitor Plus Checkpoint Blocker Tested in Advanced Lung Cancer Trial
A phase 1/2 trial combined mocetinostat and durvalumab in 83 patients with advanced solid tumors and NSCLC.
Clinical Trial
May 7, 2026 0
Longevity & Aging
Senolytic Drugs Target Aging Cells to Strengthen Bones in Elderly Women
Clinical trial tests whether senolytic compounds can reduce cellular aging burden and improve bone health markers in older adults.
Clinical Trial
Mar 28, 2026 1
Heart Health
Bempedoic Acid Plus Ezetimibe Combo Targets LDL in Diabetic Patients
A Phase 2 trial tests whether a fixed-dose combination pill can safely lower LDL cholesterol in people with type 2 diabetes.
Clinical Trial
Jun 17, 2026 0
Cancer Research
Sunitinib Shows Promise After Immunotherapy Failure in Kidney Cancer
A phase II trial tests whether sunitinib retains activity in metastatic renal cell carcinoma after first-line immunotherapy resistance.
Clinical Trial
May 25, 2026 0
Cancer Research
Triple Combo Therapy Targets Chemo-Resistant Colorectal Cancer in Phase I Trial
A completed phase I trial tests regorafenib plus dual checkpoint inhibitors in 39 patients with hard-to-treat metastatic colorectal cancer.
Clinical Trial
May 9, 2026 0
Metabolic Health
Thorne's Quercetin Phytosome Trial for Metabolic Health Was Terminated Early
A sponsored 90-day trial of enhanced-absorption quercetin targeting cholesterol, blood sugar, and metabolic age was terminated before completion.
Clinical Trial
Jun 24, 2026 0
Cancer Research
Dual Checkpoint Blockade Plus FOLFOX Chemo Tested in Metastatic Colorectal Cancer
A Phase 1/2 trial tests whether combining durvalumab, tremelimumab, and FOLFOX chemotherapy can safely boost immune response in mCRC.
Clinical Trial
May 17, 2026 0
Cancer Research
Cancer Trial Tests Novel Immune Booster BAY 2416964 With Pembrolizumab
Researchers tested a new drug combination targeting immune suppression in advanced solid tumors before early termination.
Clinical Trial
Mar 28, 2026 0
Cancer Research
Triple Immune Checkpoint Blockade Tested in Advanced Solid Tumors
A Phase 1/2 trial explores combining KIR, PD-1, and CTLA-4 inhibitors to unlock stronger anti-tumor immunity.
Clinical Trial
May 20, 2026 0
Cancer Research
Pfizer Tests Novel CD47-PD-L1 Bispecific Antibody in Advanced Solid Tumors
A first-in-human Phase 1 trial evaluates PF-07257876, a dual-checkpoint bispecific antibody targeting both CD47 and PD-L1, in hard-to-treat cancers.
Clinical Trial
May 21, 2026 0
Cancer Research
Triple Combination Cancer Immunotherapy Shows Promise in Advanced Solid Tumors
Small trial tests novel three-drug approach combining immune checkpoint inhibitor, vaccine, and inflammation blocker for metastatic cancers.
Clinical Trial
Mar 29, 2026 1
Autoimmune & Arthritis
PD-L1 Antibody ASC22 Combined With ART Shows Promise Against HIV-1
A completed Phase II trial tested the checkpoint inhibitor ASC22 alongside antiretroviral therapy to target HIV-1 immune exhaustion.
Clinical Trial
Jun 14, 2026 0
Cancer Research
Whole-Cell Breast Cancer Vaccine Plus PD-1 Inhibitor Targets Treatment-Resistant Metastatic Disease
A phase I/II trial tests SV-BR-1-GM, a whole-cell cancer vaccine, combined with the checkpoint inhibitor retifanlimab in patients with metastatic breast cancer.
Clinical Trial
May 29, 2026 0
Longevity & Aging
Fisetin Tested as Senolytic Treatment to Reduce COVID-19 Complications
A Phase 2 pilot trial investigates whether the natural senolytic compound fisetin can reduce dysfunction and complications in COVID-19 patients.
Clinical Trial
May 8, 2026 0
Cancer Research
Phase I Trial Tests Triple Drug Combo for BRAF-Mutant Metastatic Solid Tumors
MD Anderson researchers evaluated vemurafenib, cetuximab, and irinotecan together to find the optimal dose and safety profile for advanced solid tumors.
Clinical Trial
Jun 5, 2026 0
Cancer Research
Curcumin Added to Standard Chemo Tested in Metastatic Colorectal Cancer Trial
A Phase 2 trial explores whether oral curcumin can enhance Avastin/FOLFIRI chemotherapy outcomes in patients with unresectable colorectal metastases.
Clinical Trial
May 16, 2026 0
Supplements
Spermidine Supplement Shows Promise for Blood Sugar Control in Prediabetic Adults
Novel KH-1 supplement containing spermidine and probiotics tested for autophagy stimulation and glucose control in 42 prediabetic participants.
Clinical Trial
Mar 28, 2026 0
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