Novel Oral Microsphere Treats IBD and Reverses Chronic Intestinal Fibrosis
Engineered cerium-peptide microspheres show 76% reduction in IBD symptoms and 66% decrease in fibrosis markers in mouse studies.
20 articles
Engineered cerium-peptide microspheres show 76% reduction in IBD symptoms and 66% decrease in fibrosis markers in mouse studies.
A double-blind RCT finds FMT capsules added to escitalopram reduce depression scores faster via bile acid and anti-inflammatory pathways.
A specific gut bacterium produces deoxycholic acid that hijacks tumor immunity, offering new targets for breast cancer treatment.
WES identified a genetic diagnosis in nearly 1 in 4 adults with unexplained cholestatic liver disease, including genes beyond the classic PFIC spectrum.
Combined therapy restored gut health in patients who failed conventional treatments, offering new hope for refractory IBD cases.
New research in Cell Metabolism explores how gut bacteria and their metabolites regulate immune checkpoint blockade efficacy in cancer patients.
Synthetic biology meets the microbiome: designer probiotics restore gut-liver-brain balance better than rifaximin in preclinical models.
A common oat fiber supercharges anti-PD-1 checkpoint therapy by expanding a key gut microbe that produces immune-activating metabolites.
Diagnostic endoscopic resection shows promise for detecting residual esophageal cancer after neoadjuvant therapy.
Fecal microbiota transplants dramatically improved immune checkpoint inhibitor response rates in lung cancer and melanoma patients.
Researchers develop innovative fluorescent approach to combat chronic hepatitis E, offering new hope for treatment-resistant infections.
Bacterial metabolite from flavonoids protects against graft-versus-host disease while preserving anti-cancer effects in stem cell transplants.
Bacteriophages transferred during FMT may drive horizontal gene transfer, altering microbial function and antibiotic resistance in ways science has largely ignored.
A microbial enzyme from Bifidobacterium enhances anti-TNF therapy efficacy in IBD by reshaping immune regulation via histone lactylation.
New review reveals how gut microbe chemicals directly reprogram tumor immune responses through multiple pathways.
Scientists develop gut-targeted compound that protects liver and boosts nutrient absorption after small bowel surgery, offering hope where no treatments exist.
New perspective reveals why gut microbiome discoveries struggle to translate into effective clinical treatments
Scientists created smart probiotics that train immune cells to hunt down and remember glioblastoma cancer cells, achieving complete tumor elimination.
New research shows blocking PKM2 in immune cells promotes gut healing in colitis while preventing tumor formation.
Researchers identify a gut-microbe-driven pathway linking IBS-D and insulin resistance, with oleoylethanolamide as a key therapeutic molecule.