20 articles
New clinical trial shows fasting-mimicking diets enhance autophagy and improve glucose metabolism in healthy adults over just 6 days.
A randomised trial finds monthly 5-day fasting-mimicking diet cycles significantly reduce myocardial triglyceride content in type 2 diabetes patients.
A pilot trial shows a recipe-based FMD reduces body fat and IGF-1 while preserving muscle mass in breast cancer patients undergoing chemotherapy.
A 12-month trial finds a fasting-mimicking diet cuts visceral and subcutaneous abdominal fat significantly while preserving muscle mass in T2D patients.
A randomized trial finds 5-day monthly fasting cycles dramatically improve Crohn's disease remission rates and reduce gut inflammation.
New review synthesizes preclinical and clinical evidence showing fasting may sensitize tumors to chemotherapy while protecting healthy cells.
Dr Valter Longo argues the 5-day fasting-mimicking diet triggers deep cellular repair — from autophagy peaks to tissue regeneration after refeeding.
Five-year study reveals how traditional Mediterranean eating patterns combined with periodic fasting affects weight and metabolic health.
Mouse study shows FMD cycles dramatically reduce acute kidney injury and CKD progression by suppressing CCL2-driven monocyte infiltration.
A 42-woman trial shows 5-day fasting cuts leptin, insulin, and glucose while boosting ketones and mood—but psychology shapes outcomes.
A fasting-mimicking diet activates IFNβ secretion in tumor macrophages by degrading the immune suppressor Trex1 through a NRF1-driven proteasome pathway.
A 2025 integrative review finds Mediterranean, plant-based, and fasting diets reduce liver fat and metabolic dysfunction in MASLD patients.
A 6-month fasting-mimicking diet restored fat-burning flexibility and improved albuminuria in T2D patients, with metabolomics revealing who responds best.
New research reveals how alternate-day fasting triggers profound lipid saturation shifts and spatial reprogramming in brown fat via mTORC1 signaling.
University of Pittsburgh researchers weigh the science of fasting, concluding benefits are plausible but unproven—and call for rigorous human trials.
Review examines how ketogenic and fast-mimicking diets may enhance cancer treatment while reducing chemotherapy side effects.
A 2025 review of 87 studies finds prolonged fasting boosts mood and cognition in healthy adults while triggering psychiatric crises in vulnerable individuals.
A rigorous 2025 review dissects fasting biology, cardiometabolic benefits, and underappreciated bone health risks from intermittent fasting.
A detailed review maps how multi-day fasting alters key hormonal axes—with real benefits and real risks for healthspan.
A Nature study reveals fasting activates glucocorticoid receptors in breast tumors, dramatically boosting endocrine therapy and pointing to steroid drugs as a fasting substitute.
