20 articles
New research reveals intermittent fasting forces immune memory cells from their protective niches, potentially compromising long-term immunity.
Intermittent fasting reshapes gut microbiota and bile acids to reduce autoimmune inflammation in the lacrimal gland, improving dry eye in mice.
A completed French trial investigated whether rogue antibodies targeting ghrelin and alpha-MSH disrupt appetite regulation in eating disorder patients.
Natural flavonoid fisetin activates mitophagy and xenophagy pathways to restrict intracellular Salmonella growth in immune cells.
New research reveals metformin can silence HIV and boost immune control, offering hope for treatment-free remission.
A 205,000-person UK Biobank study finds the EAT-Lancet diet reduces RA risk, with omega-3s and anti-inflammatory metabolites driving one-third of the benefit.
Demethyleneberberine, derived from traditional Chinese medicine, significantly reduced lung scarring by targeting NLRP3 inflammasome and EMT in mice.
New research reveals how blood factors trigger muscle weakness in autoimmune disease and identifies potential therapeutic targets.
New research reveals how a single antibody treatment creates lasting protection against autoimmune diabetes by reshaping immune cells.
New research reveals efgartigimod reshapes B-cell populations in myasthenia gravis, inducing regulatory plasma cells linked to clinical improvement.
A phase 1/2 trial finds low-dose oral NMN safely raises platelet counts in steroid-refractory ITP via a novel immunometabolic mechanism.
Pyruvate, a core metabolic molecule, suppresses interferon signaling by directly modifying STAT1 — linking metabolism to immune control.
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
A major review maps emerging immunotherapies—from JAK inhibitors to microbiome interventions—that could transform care for celiac and food allergy patients.
New research reveals why giving multiple doses of a promising type 1 diabetes treatment doesn't improve outcomes beyond a single course.
Dying cancer cells release GPX4 protein that prevents immune system activation, revealing new immunotherapy targets.
A Phase 4 trial compares two antiretroviral strategies in treatment-naive HIV patients with dangerously low CD4 counts below 100.
A new review reveals how diet, exercise, and stress reduction can measurably reverse key markers of immune aging and inflammaging.
New research reveals how removing ZFP148 protein boosts CD8+ T cells' cancer-fighting ability and improves immunotherapy response.
Researchers develop standardized lung washing procedure that rapidly improves breathing and quality of life in patients with rare disease.
