20 articles
Eli Lilly suggests lower doses of tirzepatide may safely sustain weight loss at potentially lower cost, opening new options for long-term obesity management.
Radiation triggers a Ca²⁺-NFATc1-Fis1 cascade that fragments mitochondria in bone marrow stem cells, halting bone repair — and silencing Fis1 reverses it.
A UC Berkeley spinout is developing a one-time gene therapy using transposons to sustain GLP-1 activity — potentially replacing daily weight loss drugs.
Breakthrough crystal technology enables transplanted insulin-producing cells to survive and function for a full year without traditional immunosuppression.
New study suggests Lilly's tirzepatide leads to more lean muscle loss compared to Novo's semaglutide, despite superior weight loss results.
Blocking zinc transport in stem cell-derived pancreatic islets improves their survival and function after transplantation for diabetes treatment.
Amgen expands late-stage testing of its long-acting obesity drug MariTide, including a trial for patients switching from rival GLP-1 medications.
A sweeping review maps every known strategy for delivering therapies directly to mitochondria, from lifestyle habits to nanocarriers and gene editing.
Epicrispr's GEMS platform silences disease genes epigenetically — reversibly and safely — with a single viral vector, targeting FSHD and beyond.
Pharmaceutical giants clash over obesity drug superiority claims as Lilly's new pill gets FDA approval and Novo fights back with competing data.
Breakthrough treatment uses engineered immune cells to eliminate scar tissue and restore liver function in metabolic liver disease.
Breakthrough review reveals how modern diabetes treatments protect multiple organs and may extend healthy lifespan through novel mechanisms.
A new mitochondrial epigenetic editor silences aging-linked genes without altering DNA sequence, opening doors to programmable longevity interventions.
Revolutionary microfluidic technology could transform how new medicines are tested, making drug development faster and more accurate.
A novel bone-mimicking scaffold delivering low-dose rhBMP-2 achieved complete fracture union in 4 months in a medically complex elderly patient.
A short-term drug combo rejuvenates aged mesenchymal stem cells, boosting proliferation and reducing inflammatory markers in vitro.
New wearable and non-invasive glucose monitors are transforming diabetes care — here's what's available and how they work.
New research reveals how high blood sugar directly impairs muscle stem cells, leading to weaker muscles and poor injury recovery.
Researchers identify how host macrophages destroy foreign cells in embryos — and three strategies to stop it, boosting organ-growing chimeras.
Breakthrough organoid research reveals how to grow healthy pancreatic cells, opening new paths for cancer prevention and metabolic health.
