Fasting as Regenerative Medicine: What Dr Valter Longo's Research Reveals
Dr Valter Longo argues the 5-day fasting-mimicking diet triggers deep cellular repair — from autophagy peaks to tissue regeneration after refeeding.
20 articles
Dr Valter Longo argues the 5-day fasting-mimicking diet triggers deep cellular repair — from autophagy peaks to tissue regeneration after refeeding.
A proteomics study tracking 3,000 blood proteins reveals fasting's deepest benefits emerge only after 72 hours without food.
Historical and modern evidence suggests fasting can reverse diabetes, but sustainable dietary changes are crucial for lasting results.
Stanford study shows fasting-mimicking diet for 5 days monthly improved symptoms in two-thirds of Crohn's patients while reducing inflammation markers.
A new study finds intermittent fasting triggers coordinated changes in gut microbiome and brain regions controlling appetite and cravings.
Cochrane analysis of 22 trials finds intermittent fasting produces no meaningful weight loss advantage over conventional diet advice.
A low-calorie fasting diet reduced gum and systemic inflammation markers in periodontitis patients, pointing to diet as a powerful oral health tool.
An 8-hour feeding window extended median lifespan in male mice by 12%, though caloric restriction may explain part of the benefit.
MitoRx's MTRX31 targets mitochondrial metabolism to slash fat mass 62% in mice while preserving muscle — no hunger suppression needed.
Reducing protein to recommended levels may double the longevity hormone FGF21, improving fat loss and insulin sensitivity within weeks.
FGF21 extends lifespan in animals by 30-40%. Here's what exercise and diet research reveals about boosting it naturally.
University of Sydney researchers found that cutting fat or animal protein for just four weeks lowered biological age markers in older adults.
MetaVia's dual-action GLP-1/glucagon receptor drug DA-1726 shows rapid, sustained weight loss in Phase 1 trials with a strong safety profile.
Reducing methionine and cysteine in diet activated calorie-burning beige fat as effectively as cold exposure, offering new weight loss insights.
New research shows extreme calorie restriction alone matches bariatric surgery's diabetes reversal benefits without surgical risks.
New evidence shows meal timing — not just meal content — significantly impacts blood sugar, insulin resistance, and metabolic health.
New research shows people who stick to consistent meals and steady calories lose significantly more weight than those who vary their food choices.
New research reveals how hormone FGF21 activates brain circuits to boost metabolism and reverse obesity, offering alternative to GLP-1 drugs.
New research shows ketogenic diet helps normalize blood sugar and dramatically improves muscle response to exercise in mice.
New research shows blood sugar can normalize without losing weight by shifting harmful belly fat to healthier locations under the skin.