Why Fenofibrate Outperforms Other Fibrates for Cardiovascular Risk
Not all fibrates work the same way โ fenofibrate uniquely reduces apoB, cutting residual cardiovascular risk beyond statins alone.
20 articles
Not all fibrates work the same way โ fenofibrate uniquely reduces apoB, cutting residual cardiovascular risk beyond statins alone.
New research shows inhibiting fatty acid synthase prevents cardiac hypertrophy and restores heart function in multiple models.
New research reveals finerenone may reduce new-onset atrial fibrillation in heart failure patients with preserved ejection fraction.
Dive deep into the molecular mechanisms of vascular aging and explore cutting-edge interventions โ from senolytic therapies and nitric oxide restoration to exercise-induced remodeling and emerging pharmacological approaches โ that are redefining what's possible in cardiovascular longevity.
A sirtuin enzyme prevents heart scarring by keeping cardiac fibroblasts from switching to a pro-fibrotic metabolic state.
Natural isoflavone prevents cardiac enlargement through novel mitochondrial protection pathway, offering new therapeutic approach.
A comprehensive review reveals tirzepatide improves blood pressure, lipids, liver fat, kidney function, and slashes 10-year cardiovascular risk by up to 23.5%.
Sotatercept emerges as potential treatment for combined pre-capillary pulmonary hypertension and heart failure with preserved ejection fraction.
Isoquercitrin reshapes gut bacteria and tryptophan metabolism to reduce arterial plaque, pointing to a novel gut-heart therapeutic pathway.
First new COPD medication in over a decade targets dual pathways to improve breathing and reduce inflammation.
New research shows GDF11, an anti-aging protein, prevents dangerous calcium buildup in arteries by suppressing inflammatory pathways.
A new review reveals how sirtuin enzymes regulate cardiac fibrosis and why targeting them could reshape heart failure treatment.
The first disease-specific treatment for Barth syndrome gains FDA accelerated approval, targeting mitochondrial dysfunction to restore muscle strength.
New study shows clearing senescent cells with Navitoclax improves heart function and reduces inflammation in heart failure with preserved ejection fraction.
A Phase 2 trial tests whether a fixed-dose combination pill can safely lower LDL cholesterol in people with type 2 diabetes.
Merck's CETP inhibitor anacetrapib was evaluated alongside statin therapy to assess LDL-C lowering and HDL-C raising in hypercholesterolemia patients.
Pfizer's landmark trial examines whether tafamidis can safely treat transthyretin amyloid cardiomyopathy, a progressive and often fatal heart condition.
Major study shows tirzepatide reduces cardiovascular and kidney complications by 16% compared to dulaglutide in diabetic patients.
Real-world study of 1,559 octogenarians finds SGLT2 inhibitors reduce all-cause death by 42% and heart failure rehospitalization by 31% with no increase in adverse events.
Dr. Terry Simpson brings personal experience with FH, tirzepatide, and statins to a blunt takedown of health misinformation.
Advanced therapies like PCSK9 and ANGPTL3 inhibitors offer hope for kids with familial hypercholesterolemia when statins aren't enough.