Results for "Fisetin Senolytic" in Diabetes

20 articles

SGLT2 Inhibitors May Slow Aging by Clearing Senescent Cells
Metabolic Health

SGLT2 Inhibitors May Slow Aging by Clearing Senescent Cells

Diabetes drugs like empagliflozin show surprising anti-aging effects β€” mimicking caloric restriction and reducing senescent cell burden.

Research Paper
May 15, 2026 0
Finerenone Slows Kidney Decline in Non-Diabetic CKD Patients
Metabolic Health

Finerenone Slows Kidney Decline in Non-Diabetic CKD Patients

A landmark RCT shows finerenone reduces eGFR decline and kidney-cardiovascular events in CKD patients without diabetes.

Research Paper
Jun 8, 2026 0
Phosphatidylserine Supplement Improves Liver Health and Blood Sugar Control in Mice
Metabolic Health

Phosphatidylserine Supplement Improves Liver Health and Blood Sugar Control in Mice

New research shows phosphatidylserine supplementation reduces liver fat and inflammation while improving glucose control through enhanced fat metabolism.

Research Paper
Mar 29, 2026 3
Marine Compound Enterocin Lowers Cholesterol by Targeting Liver Protein ASGR1
Metabolic Health

Marine Compound Enterocin Lowers Cholesterol by Targeting Liver Protein ASGR1

Natural polyketide from marine bacteria enhances cholesterol removal and improves fat metabolism in liver cells and mice.

Research Paper
Mar 29, 2026 2
SGLT2 Inhibitor Dapagliflozin Reshapes Metabolism Beyond Blood Sugar Control
Metabolic Health

SGLT2 Inhibitor Dapagliflozin Reshapes Metabolism Beyond Blood Sugar Control

New study reveals how the diabetes drug dapagliflozin dramatically alters fat metabolism and kidney function through previously unknown pathways.

Research Paper
Apr 9, 2026 0
GLP-1 Drugs Show Liver Benefits in Fatty Liver Disease Beyond Weight Loss
Metabolic Health

GLP-1 Drugs Show Liver Benefits in Fatty Liver Disease Beyond Weight Loss

Updated review of anti-obesity medications in MASLD finds GLP-1 agonists reduce steatosis and fibrosis, while newer dual/triple agonists show even greater metabolic promise.

Research Paper
Jun 4, 2026 0
Semaglutide protects liver through direct action on blood vessel cells, not weight loss
Metabolic Health

Semaglutide protects liver through direct action on blood vessel cells, not weight loss

New research reveals semaglutide's liver benefits work independently of weight loss through specialized liver blood vessel cells.

Research Paper
Apr 16, 2026 0
New Dual-Target Drug Amycretin Achieves 24% Weight Loss in Clinical Trials
Metabolic Health

New Dual-Target Drug Amycretin Achieves 24% Weight Loss in Clinical Trials

Novel obesity drug targeting two pathways simultaneously shows unprecedented weight loss results in recent clinical studies.

Research Paper
Mar 28, 2026 1
New Protein Target Could Unlock FGF21's Power Against Fatty Liver Disease
Metabolic Health

New Protein Target Could Unlock FGF21's Power Against Fatty Liver Disease

Scientists discover how FGF21 fights liver disease through a key protein, opening new treatment paths for metabolic dysfunction.

Research Paper
Apr 3, 2026 0
Nanoplastics Accumulate in Mouse Testes and Trigger Sperm-Killing Ferroptosis via CISD1
Metabolic Health

Nanoplastics Accumulate in Mouse Testes and Trigger Sperm-Killing Ferroptosis via CISD1

50 nm polystyrene nanoplastics accumulate in mouse testes, degrading sperm quality and triggering iron-dependent cell death through a newly identified mitochondrial pathway.

Research Paper
Jun 20, 2026 0
New Injectable Drug Cuts Cholesterol 28% in Teens With Genetic High Cholesterol
Metabolic Health

New Injectable Drug Cuts Cholesterol 28% in Teens With Genetic High Cholesterol

Inclisiran safely reduced LDL cholesterol by 28% in adolescents with familial hypercholesterolemia, offering hope for early intervention.

Research Paper
Mar 29, 2026 0
Cold Exposure Plus Exercise Beats Either Alone for Reversing Fatty Liver
Metabolic Health

Cold Exposure Plus Exercise Beats Either Alone for Reversing Fatty Liver

Combining cold exposure with exercise activates a key metabolic pathway to reduce liver fat and fibrosis more effectively than either intervention alone.

Research Paper
May 4, 2026 0
Beta-Hydroxybutyrate Protects Liver from Sepsis Through Novel Protein Modification
Metabolic Health

Beta-Hydroxybutyrate Protects Liver from Sepsis Through Novel Protein Modification

Ketone body Ξ²-OHB prevents sepsis-induced liver damage by modifying antioxidant enzyme SOD2, offering new therapeutic approach.

Research Paper
Apr 4, 2026 0
Cholesterol Drug Bempedoic Acid Activates Key Fat-Burning Pathway in Liver Cells
Metabolic Health

Cholesterol Drug Bempedoic Acid Activates Key Fat-Burning Pathway in Liver Cells

New research reveals how the cholesterol medication bempedoic acid directly activates PPARΞ±, boosting fat metabolism beyond its known effects.

Research Paper
Mar 29, 2026 3
Tirzepatide Cuts Key Inflammation Markers by Up to 34% in Meta-Analysis
Metabolic Health

Tirzepatide Cuts Key Inflammation Markers by Up to 34% in Meta-Analysis

A systematic review of 8 studies finds tirzepatide significantly reduces hsCRP and IL-6 across all doses and populations.

Research Paper
May 30, 2026 0
Scientists Discover Key Protein That Drives Liver Scarring and Potential Treatment Target
Metabolic Health

Scientists Discover Key Protein That Drives Liver Scarring and Potential Treatment Target

New research reveals how SREBP2 protein triggers liver fibrosis through metabolic changes, offering hope for treating liver disease.

Research Paper
Mar 28, 2026 1
New Skincare Protocol Combats GLP-1 Weight Loss Drug Side Effects on Facial Aging
Metabolic Health

New Skincare Protocol Combats GLP-1 Weight Loss Drug Side Effects on Facial Aging

Flavo-Proxylane topical treatment plus ultrasound reduced skin laxity by 44% in people using weight loss medications.

Research Paper
Mar 28, 2026 3
New PKU Drug Sepiapterin Shows 70% Better Results Than Current Standard Treatment
Metabolic Health

New PKU Drug Sepiapterin Shows 70% Better Results Than Current Standard Treatment

Breakthrough study reveals sepiapterin dramatically outperforms existing PKU therapy, offering hope for better metabolic control.

Research Paper
Mar 29, 2026 3
MASH Treatment Revolution: Semaglutide, Tirzepatide Lead a New Drug Era
Metabolic Health

MASH Treatment Revolution: Semaglutide, Tirzepatide Lead a New Drug Era

A landmark JCI review maps the expanding pharmacological arsenal for MASH, from GLP-1 agonists to triple receptor therapies and precision medicine.

Research Paper
May 30, 2026 0
Cytochrome c Protein Blocks Ferroptosis Cell Death Linked to Aging and Disease
Metabolic Health

Cytochrome c Protein Blocks Ferroptosis Cell Death Linked to Aging and Disease

New research reveals how a key cellular protein prevents ferroptosis, a type of cell death implicated in aging and age-related diseases.

Research Paper
Mar 29, 2026 3
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