20 articles
Single-cell analysis reveals how the flavonoid fisetin may reduce neuroinflammation in Alzheimer's disease by targeting specific astrocyte subgroups.
Breakthrough antisense therapy demonstrates sustained benefits for rare genetic form of ALS in extended clinical trial.
A naturally occurring fatty acid amide activates immune cells in the retina, protecting neurons and blood vessels from degenerative damage.
Researchers discover a phospholipid derivative that protects brain cells by calming overactive immune cells in dementia-prone mice.
Scientists identify ferroptosis as a key driver of Alzheimer's disease, opening doors to iron-based prevention therapies.
AI-driven study identifies ฮฑ-amyrin from fruits and vegetables as a promising Alzheimer's treatment that protects mitochondria and reduces tau tangles.
A 3-month fish hydrolysate supplement significantly improved episodic memory in healthy seniors showing accelerated cognitive decline, with reduced inflammation markers.
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
Pomegranate metabolite urolithin A reduced brain damage and improved recovery in mouse stroke model by blocking inflammation and cell death.
New drug FP802 disrupts toxic brain signaling, preventing memory loss and brain damage in Alzheimer's mouse models.
SOMCL-668 improved memory and reduced brain damage in Alzheimer's mice by targeting sigma-1 receptors and protective pathways.
Study shows 2'-fucosyllactose improves cognitive function in mice by modulating gut microbiota and brain serotonin levels.
Editorial raises concerns about influential 2009 study on Cerebrolysin's effects on brain degeneration in Alzheimer's models.
New research reveals how spermine promotes protein condensation and autophagy to combat neurodegeneration in lab models.
New study reveals brain blood vessel aging as key driver of memory loss, with senolytic drugs showing promise for reversal.
Promising Cerebrolysin research for rare neurological disorder withdrawn, highlighting research integrity concerns.
Cerebral hypoperfusion drives glymphatic dysfunction in systemic inflammation โ and restoring blood flow with levosimendan reverses it.
Researchers built a machine learning imaging pipeline to detect cerebral microhemorrhages and tested SS-31 (elamipretide) in aged hypertensive mice.
Synthetic peptide chimeras degrade amyloid-beta across the blood-brain barrier, improving cognition in mice with fewer risks than current immunotherapies.
