20 articles
Single-cell analysis reveals how the flavonoid fisetin may reduce neuroinflammation in Alzheimer's disease by targeting specific astrocyte subgroups.
Cassava Sciences' 76-week Phase 3 trial of simufilam for Alzheimer's was terminated, raising questions about the drug's future.
Breakthrough antisense therapy demonstrates sustained benefits for rare genetic form of ALS in extended clinical trial.
A completed Phase 1/2 pilot trial tested whether the senolytic duo D+Q penetrates the brain in early Alzheimer's disease.
New mouse research finds the trendy D+Q senolytic combo severely damages myelin, raising red flags for longevity self-experimenters.
A naturally occurring fatty acid amide activates immune cells in the retina, protecting neurons and blood vessels from degenerative damage.
A Phase 2 open-label trial explores whether an approved immune drug can raise frataxin protein levels and slow neurological decline in Friedreich Ataxia.
Researchers discover a phospholipid derivative that protects brain cells by calming overactive immune cells in dementia-prone mice.
Scientists identify ferroptosis as a key driver of Alzheimer's disease, opening doors to iron-based prevention therapies.
AI-driven study identifies ฮฑ-amyrin from fruits and vegetables as a promising Alzheimer's treatment that protects mitochondria and reduces tau tangles.
A 3-month fish hydrolysate supplement significantly improved episodic memory in healthy seniors showing accelerated cognitive decline, with reduced inflammation markers.
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
24-week trial tested fucoxanthin-rich microalgae supplement on memory, attention, and executive function in 66 healthy seniors.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
Italian researchers test plant-based compounds for brain health and quality of life in aging adults with promising early results.
Pomegranate metabolite urolithin A reduced brain damage and improved recovery in mouse stroke model by blocking inflammation and cell death.
New research identifies FTL1 protein as key driver of brain aging. Reducing it restored memory and neural connections in mice.
Radix Bupleuri restores liver health by fixing bile acid balance and activating key metabolic pathways in animal studies.
New drug FP802 disrupts toxic brain signaling, preventing memory loss and brain damage in Alzheimer's mouse models.
SOMCL-668 improved memory and reduced brain damage in Alzheimer's mice by targeting sigma-1 receptors and protective pathways.
