20 articles
Comprehensive review examines peptides like BPC-157 and TB-500 for wound healing, muscle repair, and recovery optimization in orthopedic medicine.
Researchers used prime editing to introduce and then correct a de novo GDF11 nonsense mutation, revealing Golgi stress and broad transcriptomic dysregulation.
New research reveals that targeting a specific toxic protein variant may be more effective than current Huntington's treatments.
New hydrogel combining copper ions with plant compound dramatically improves diabetic wound healing in mice studies.
A special issue overview surveys three decades of peptide-based materials research, spotlighting applications from drug delivery to regenerative medicine.
Epicrispr's GEMS platform silences disease genes epigenetically โ reversibly and safely โ with a single viral vector, targeting FSHD and beyond.
Novel mineralized collagen scaffold promotes healing of tendon-bone connections across multiple animal models with 82% recovery rate.
Computational protein design produces potent GPCR-targeting miniproteins for pain, cancer, obesity, and migraine with in vivo efficacy.
New research identifies a drug target that could help millions of fractures heal properly when blood flow is compromised.
Dihydrotestosterone treatment restored heart function in aging mice by activating DNA repair mechanisms and reducing inflammation.
Harvard-developed ENTER nanoparticles outperform lipid transfection reagents in delivering mRNA, CRISPR, proteins, and siRNA to diverse cell types.
New research reveals how activating HDAC5 enzyme accelerates wound healing, offering hope for diabetic and chronic wounds.
Researchers used AI protein design to rebuild prime editor enzymes, achieving up to 2.9-fold better genome editing in mice.
The transcription factor Lhx2 in liver stellate cells promotes regeneration and suppresses fibrosis via TGF-ฮฒ and HGF pathways.
A new nanopore-based approach aims to sequence peptides by reversing the translation process, potentially transforming proteomics.
Researchers develop innovative method to guide immune cells to pancreatic tumors using engineered viruses and targeted cytokines.
New research shows GDF11 protein can prevent and treat steroid-induced bone death by activating blood vessel formation pathways.
Scientists discover NKX6.1 gene expression can predict which pancreatic islet transplants will succeed in treating type 1 diabetes.
Researchers engineer tissue-targeting lipid nanoparticles that precisely deliver mRNA and prime editing tools to lungs, liver, spleen, thymus, and bone.
CRISPR gene editing successfully prevented heart failure in mice by disabling a key protein that drives cardiac damage.
