20 articles
A 4-week pilot trial finds nicotinamide riboside boosts cerebrovascular response and cognitive performance in older adults with peripheral artery disease.
New study reveals brain imaging can identify which people with mild cognitive impairment respond best to targeted interventions.
A completed pharmacokinetic study tracks NAD precursors NR and NMN from bloodstream to brain, filling a critical gap in human data.
A completed pilot trial tests whether 2g/day of a novel carnosine formulation can restore neuromuscular function and quality of life in MS patients.
NGP 555 targets toxic brain protein production in healthy volunteers, offering potential early intervention for Alzheimer's prevention.
New review reveals how combining citicoline, CoQ10, and other agents may protect retinal cells better than single treatments.
A surprising new role for brain immune cells: microglia orchestrate glucose delivery to fuel memory-forming protein synthesis in active neurons.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
New research reveals how targeting the brain's glymphatic drainage system might remove harmful ฮฑ-synuclein buildup in Parkinson's disease.
New mouse study reveals how the brain's waste-clearance system modulates toxic protein buildup linked to Parkinson's disease.
Microglia package healthy mitochondria into vesicles and deliver them to astrocytes, sharply reducing cognitive decline in tau-pathology mice.
A completed trial tests whether daily Nordic berry beverages can sharpen cognition in healthy adults over 12 weeks.
Master the molecular architecture of glymphatic and meningeal lymphatic systems โ from AQP4 gating mechanisms to VEGF-C therapy โ and explore the cutting-edge interventions targeting these pathways for neurodegeneration prevention.
After ischemic stroke, a mislocated brain water channel (AQP4) disrupts waste clearance. Blocking AQP4 with TGN-020 corrects its position and restores glymphatic flow.
New research reveals how glucose availability directs brain cell proliferation via a metabolic-epigenetic axis, with implications for MS and brain repair.
Comprehensive review examines dietary approaches like gluten-free, ketogenic, and supplement protocols for ASD symptom management.
AAV delivery of AIBP protein restores cholesterol balance, silences inflammation, and preserves vision in glaucoma models.
Arginine supplements reduced toxic amyloid buildup, brain inflammation, and behavioral decline in fly and mouse Alzheimer's models.
A novel brain organoid stress model reveals how combining walnut peptide and theanine activates BDNF pathways to reduce anxiety and boost cognition.
Losing a key cholinergic peptide dramatically worsens memory in Alzheimer's mice, pointing to a overlooked pathway in cognitive decline.
