20 articles
Scientists discover how tumor lactate weakens immune cells and identify supplement combo that restores cancer-fighting power.
Redirecting glucose metabolism during T cell expansion dramatically improves cancer immunotherapy effectiveness.
New research reveals how hepatoma cells evade immunotherapy by secreting N1-acetylspermidine to suppress immune function.
Engineered green tea compound nanoparticles activate cellular powerhouses to suppress tumor growth and improve immune response against melanoma.
A growth factor called GDF11 reprograms pro-tumor macrophages by rewiring their metabolism, suppressing hepatocellular carcinoma growth.
A counterintuitive mechanism shows that more NECTIN4 antigen on tumor cells can actually blunt antibody-drug conjugate therapy.
A macrophage-derived metabolite rewires tumor metabolism and flips immune cells from tumor-promoting to tumor-fighting.
A newly identified enzyme links lactate metabolism to liver cancer progression, and a natural compound delivered via nanoparticles shows striking anti-tumor results.
Novel nanoparticle combines protein degrader with light therapy to reprogram cancer metabolism and eliminate breast tumors.
New research reveals how ฮฑ-ketoglutarate regulates AMPK synthesis, offering potential cancer therapy targets through energy stress.
Scientists discover how to reprogram cancer cells into harmless, non-dividing cells by targeting a nuclear enzyme pathway.
Ginsenoside Rh4 suppresses colorectal cancer by boosting Akkermansia muciniphila and elevating protective bile acid UDCA via FXR signaling.
McGill scientists boosted NK cell cancer-killing power using reversible drug treatment, targeting leukemia, glioblastoma, and triple-negative breast cancer.
Adding an autophagy inhibitor to anlotinib plus PD-1 blockade dramatically reshapes the tumor microenvironment in NSCLC models.
Advanced gastric cancer treatments using immunotherapy and targeted drugs extend survival by 3-4 months beyond traditional chemotherapy.
Metabolite supplement protects heart from chemo toxicity and enhances tumor suppression in breakthrough dual-action study.
Researchers respond to peer critique of risk-based, non-invasive hepatocellular carcinoma surveillance in metabolic liver disease patients.
New review reveals how neurotransmitters like norepinephrine and acetylcholine directly regulate immune cells in tumors, opening therapeutic targets.
A phase II trial explores whether the amino acid L-arginine, with or without enzyme inhibitors, can improve erectile function and quality of life after prostate cancer radiation therapy.
Lactobacillus johnsonii bacteria enhances immune response and prevents liver cancer recurrence when combined with immunotherapy.
