20 articles
Review reveals how NAD+ precursors like NMN could restore heart function by fixing cellular energy production and reducing oxidative damage.
A Phase 1/2 trial tests whether nicotinamide riboside can restore NAD+ balance and improve heart function in systolic HF patients.
High-dose nicotinamide riboside increased atherosclerotic plaques and inflammation in mice, challenging NAD+ supplement safety.
Scientists uncover how faulty glycogen-priming proteins cause progressive cardiomyopathy, pointing toward gene therapy and autophagy as future treatments.
Scientists map a precise molecular chain linking falling NAD levels to lysosomal dysfunction, cardiolipin loss, and age-related heart failure โ and show NAD restoration can reverse it.
New research reveals NAD metabolism governs how blood vessels stabilize after growth, with implications for cancer and eye disease.
A phase 3 trial adding ERN/LRPT to statin therapy for dyslipidemia was terminated early, raising questions about the drug's clinical future.
New research shows citrate supplementation restores blood vessel function and extends lifespan by improving mitochondrial health.
Scientists identify GPRASP1 as a key guardian of pulmonary vascular health, opening a potential drug target for PH-HFpEF.
GLP-1 drug semaglutide demonstrates potential benefits for Alzheimer's patients following major clinical trial results.
New study shows clearing senescent cells with Navitoclax improves heart function and reduces inflammation in heart failure with preserved ejection fraction.
Dr. Jamnadas explains how vagus nerve activation directly improves digestive health and gut healing through specific mechanisms.
A muscle enzyme that declines in heart attack patients may hold the key to preserving cardiac function after MI.
Clinical trial shows memantine reduces premature atrial contractions by 47% and prevents atrial fibrillation in heart patients.
Dr. Jamnadas reveals which foods can protect against AGEs, the hidden compounds in our diet that speed up aging and disease.
A newly discovered mitochondrial protein boosts cardiac glucose burning and dramatically reduces heart injury after ischemia-reperfusion.
Dive deep into the molecular mechanisms of vascular aging and explore cutting-edge interventions โ from senolytic therapies and nitric oxide restoration to exercise-induced remodeling and emerging pharmacological approaches โ that are redefining what's possible in cardiovascular longevity.
Scientists discover targeting two cellular pathways simultaneously could overcome treatment resistance in neuroendocrine tumors.
A 330-patient multicenter RCT tests whether thymosin ฮฑ1 can curb immune dysregulation and organ dysfunction after acute type A aortic dissection repair.
New research reveals GLP-1 receptor agonists could significantly reduce cardiovascular risk in broader patient populations.
