20 articles
Novel biomaterial treatment simultaneously prevents nerve degeneration and promotes regeneration, preserving visual function after optic nerve injury.
Novel nanogel therapy targets mitochondrial ROS to break the inflammation-hypoxia cycle in periodontitis, showing strong preclinical results.
Mitochondria-targeted antioxidant polymer shows superior protection against liver transplant injury compared to standard treatments.
Three days of GDF11 infusion post-injury preserved pericytes, protected the blood-spinal cord barrier, and improved functional recovery in mice.
Novel nanoparticle therapy converts inflammatory macrophages into healing cells that deliver healthy mitochondria to damaged spinal discs.
ProcyanidinC1, a natural senolytic, selectively eliminates senescent cells in diabetic skin, dramatically improving wound healing in mouse models.
Revolutionary nanotechnology approaches demonstrate 30% better drug delivery and enhanced muscle regeneration in preclinical studies.
A phase 1 dose-escalation trial tests the safety of AAV-delivered ND4 gene therapy in patients with Leber's hereditary optic neuropathy.
Researchers discovered how GAS6 protein rejuvenates aged stem cells, potentially revolutionizing diabetic wound treatment and anti-aging medicine.
Combining nanoparticles with mesenchymal stem cells could finally overcome the poor survival and differentiation that limits cartilage regeneration.
Study shows intensive glucose management increases cardiac stem cells in heart attack patients, potentially improving recovery.
Revolutionary delivery system uses microscopic gel capsules to transport healthy mitochondria to damaged heart cells after heart attack.
Injectable hydrogel from traditional Chinese herbs shows superior wound repair by regulating immune response and promoting tissue regeneration.
Breakthrough prodrug technology enables oral delivery of allopregnanolone, showing promise for treating anxiety and mood disorders.
Blocking zinc transport in stem cell-derived pancreatic islets improves their survival and function after transplantation for diabetes treatment.
Breakthrough crystal technology enables transplanted insulin-producing cells to survive and function for a full year without traditional immunosuppression.
Revolutionary 3D culture system dramatically improves stem cell gene therapy outcomes, enhancing cell survival and therapeutic potential.
A Phase 1/2 trial of NFS-02 gene therapy for LHON-associated vision loss was terminated before completion, raising questions about mitochondrial gene therapy.
A novel anti-swelling hydrogel loaded with dasatinib, quercetin, and nucleus pulposus exosomes clears senescent cells and restores disc integrity in rats and goats.
Blocking the AhR receptor promotes axon regeneration and functional recovery in spinal cord and peripheral nerve injuries.
