51 articles
Men with Klinefelter syndrome (XXY) show reduced epigenetic aging compared to typical XY males, challenging assumptions about chromosome disorders.
Study of 1,014 adults finds GrimAge epigenetic clock most accurately links biological aging to physical performance from age 20-104.
Analysis of 1,942 people shows GrimAge and GrimAge2 epigenetic clocks outperform other aging biomarkers at predicting mortality.
New research shows DNA methylation patterns can predict biological aging in joints, offering potential biomarkers for osteoarthritis progression.
Dr. Steve Horvath explains how epigenetic clocks measure biological aging and predict healthspan better than chronological age.
Epigenetic aging markers outperformed traditional risk assessment tools in predicting lung cancer among smokers.
Researchers analyzed 12 epigenetic aging algorithms in 2,532 adults, finding GrimAge clocks best predict cancer risk over 17 years.
Major review reveals functional biomarkers outperform molecular aging clocks for predicting mortality and disease risk.
New review reveals how shared aging mechanisms drive multiple diseases, opening doors to therapies that extend healthspan rather than treat single conditions.
Large US study reveals epigenetic aging markers, especially GrimAge, predict death better than telomere length across racial groups.
Dutch twin study reveals blood-based epigenetic age acceleration correlates with brain MRI aging, driven by environmental factors.
Study of 2,939 childhood cancer survivors reveals how accelerated aging explains up to 35% of treatment-related heart disease risk.
