New Histone Lactylation Sites Drive Breast Cancer Growth Through Metabolic Loop
Scientists discover two new histone modifications that create a self-reinforcing cycle promoting breast cancer progression.
20 articles
Scientists discover two new histone modifications that create a self-reinforcing cycle promoting breast cancer progression.
New research reveals how a cancer-promoting protein reprograms cellular fat production to accelerate tumor progression.
A tryptophan-derived gut metabolite suppresses colorectal cancer by blocking a key glycolysis enzyme via STAT3 inhibition.
A large French cohort study reveals conjugated bile acids raise breast cancer risk while vitamin K intake may be protective via metabolic pathways.
Scientists discover how tumor lactate weakens immune cells and identify supplement combo that restores cancer-fighting power.
New research identifies HBO1 as a key driver of cancer cell transformation and resistance to CAR-T cell therapy in ovarian cancer.
A growth factor called GDF11 reprograms pro-tumor macrophages by rewiring their metabolism, suppressing hepatocellular carcinoma growth.
New research reveals popular weight-loss medications may reduce cancer risk beyond their metabolic benefits.
Researchers used advanced genetic analysis to find LGALS9 and SELL genes causally linked to aggressive brain tumors, revealing new treatment targets.
New research reveals how breast cancer cells exploit fatty acids in lung tissue to enhance survival and metastasis.
Engineered magnetotactic bacteria delivered orally penetrate colorectal tumors, trigger immune attack, and reshape gut microbial metabolism in mice.
Metabolite supplement protects heart from chemo toxicity and enhances tumor suppression in breakthrough dual-action study.
New research reveals how a common gut bacterium reprograms immune cells to accelerate colorectal cancer progression.
Specific gut microbes produce compounds that reprogram fat cells to enhance immune responses against cancer.
Researchers developed rat and mouse models mimicking early and middle stages of oral submucous fibrosis using bleomycin injections.
A comprehensive review in CA Cancer J Clin maps the molecular biology, treatment strategies, and equity gaps in high-grade serous ovarian cancer.
Lactobacillus johnsonii bacteria enhances immune response and prevents liver cancer recurrence when combined with immunotherapy.
MAIT cells appear to provide protective immune surveillance in Lynch syndrome carriers who haven't developed colorectal cancer, suggesting new risk stratification tools.
Researchers find that combining Ganoderma lucidum and Sanghuangporus vaninii extracts may fight colorectal cancer through vitamin D and Wnt pathways.
New 3-D spatial mapping reveals four distinct immune-evasion niches in osteosarcoma that explain why checkpoint therapies fail.