Cancer Research
Engineered Immune Cells Show Promise Against Advanced Cancer in Early Trial
Scientists modified patients' immune cells to better recognize and attack cancer tumors expressing NY-ESO-1 protein.
Clinical Trial
Mar 28, 2026 0
Results for "Immunosenescence Reversal" in Cancer
20 articles
Cancer Research
Modified T Cells Show Promise Against Childhood Blood Cancers in NCI Trial
Researchers modified children's own immune cells to fight B-cell leukemia and lymphoma when standard treatments failed.
Clinical Trial
Mar 28, 2026 0
Cancer Research
Enhanced CAR-T Cell Therapy Shows Promise Against Treatment-Resistant Blood Cancers
Modified immune cells engineered to overcome cancer's defenses completed safety testing in lymphoma patients.
Clinical Trial
Mar 29, 2026 12
Cancer Research
PULSAR Radiation Plus IMSA101 Immunotherapy Trial in Oligoprogressive Cancers Terminated Early
A Phase 2 trial combining adaptive stereotactic radiotherapy with IMSA101 and checkpoint inhibitors was halted after enrolling only 16 patients.
Clinical Trial
May 14, 2026 0
Cancer Research
Trial Tests Whether Stopping Immunotherapy Early Harms NSCLC Patients Who Respond
A randomized Phase 2 trial investigates whether PD-1 inhibitor discontinuation after early response is safe in non-small cell lung cancer.
Clinical Trial
Jun 14, 2026 0
Cancer Research
Brain Cancer Trial Uses Patient's Own Tumor Cells to Train Immune System
Innovative immunotherapy approach converts patient tumor cells into personalized vaccines to fight aggressive brain cancer.
Clinical Trial
Mar 28, 2026 0
Cancer Research
Melanoma Drug Resistance Linked to Cellular Communication Vesicles Called Exosomes
French researchers studied how tiny cellular packages called exosomes may help melanoma cells resist treatment and spread throughout the body.
Clinical Trial
Mar 28, 2026 0
Cancer Research
Strength Training Fights Inflammaging in Bone Marrow Transplant Survivors
A 10-week supervised strength program targets chronic inflammation and self-efficacy in long-term allogeneic HCT survivors.
Clinical Trial
May 25, 2026 0
Cancer Research
High-Dose Radiation Therapy Study Reveals Immune System Response Patterns in Cancer
Researchers tracked immune changes during intensive radiation treatment to optimize cancer therapy and potential immunotherapy combinations.
Clinical Trial
Mar 28, 2026 2
Cancer Research
New Cancer Immunotherapy IBI346 Shows Promise in Multiple Myeloma Trial
Small trial tests innovative treatment IBI346 for blood cancer patients who didn't respond to standard therapies.
Clinical Trial
Mar 28, 2026 1
Cancer Research
Skin Microbiome Shifts Detected in Immunotherapy Rash Patients
A City of Hope study explores whether skin bacteria differ between rash-affected and healthy skin in cancer immunotherapy patients.
Clinical Trial
Jun 6, 2026 0
Cancer Research
Cancer Immunotherapy May Weaken Bones in Melanoma Survivors
Study examines bone density loss in melanoma patients receiving immune-boosting cancer drugs like nivolumab and pembrolizumab.
Clinical Trial
Mar 29, 2026 1
Cancer Research
Engineered T Cells Show Promise Against Childhood Cancers in Phase I Trial
Modified immune cells targeting GD2 protein demonstrated safety in treating aggressive childhood cancers like neuroblastoma and osteosarcoma.
Clinical Trial
Mar 28, 2026 0
Cancer Research
Whole-Cell Breast Cancer Vaccine Plus PD-1 Inhibitor Targets Treatment-Resistant Metastatic Disease
A phase I/II trial tests SV-BR-1-GM, a whole-cell cancer vaccine, combined with the checkpoint inhibitor retifanlimab in patients with metastatic breast cancer.
Clinical Trial
May 29, 2026 0
Cancer Research
T-VEC Plus Pembrolizumab Tested in Melanoma After Anti-PD-1 Failure
Phase 2 trial explores whether combining oncolytic virus therapy with immunotherapy can rescue patients whose melanoma progressed on PD-1 blockade.
Clinical Trial
May 29, 2026 0
Cancer Research
Triple Immunotherapy Combo for Recurrent SCLC Terminated After Enrolling 9 Patients
A phase I/II trial combining nivolumab, ipilimumab, and lurbinectedin for relapsed SCLC was terminated early, raising questions about feasibility.
Clinical Trial
May 16, 2026 0
Cancer Research
Triple Immune Checkpoint Blockade Tested in Advanced Solid Tumors
A Phase 1/2 trial explores combining KIR, PD-1, and CTLA-4 inhibitors to unlock stronger anti-tumor immunity.
Clinical Trial
May 20, 2026 0
Cancer Research
Immunotherapy Before Surgery Shows Promise for Advanced Melanoma Treatment
Phase II trial tests checkpoint inhibitors given before surgery to shrink tumors and improve outcomes in stage III-IV melanoma patients.
Clinical Trial
Mar 28, 2026 0
Cancer Research
Turin Study Maps Why Multiple Myeloma Escapes Anti-CD38 Immunotherapy
Italian researchers track genomic and cellular changes in myeloma patients to uncover why anti-CD38 treatments stop working.
Clinical Trial
Jun 16, 2026 0
Cancer Research
Pfizer Terminates Phase 1 Trial of Novel Anti-PD-1/IL-15 Fusion Protein in Solid Tumors
Pfizer's first-in-human trial of PF-07209960, a dual-action immunotherapy fusion protein, was terminated after enrolling 37 patients.
Clinical Trial
May 14, 2026 0
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