New Immune Engineering Approach Shows Promise for Diabetes Islet Transplants
Researchers explore targeted immune strategies to improve pancreatic islet transplant success rates for diabetes treatment.
20 articles
Researchers explore targeted immune strategies to improve pancreatic islet transplant success rates for diabetes treatment.
Researchers shift from systemic B-cell targeting to localized immune control, potentially improving transplant success rates.
A 6-month AI-driven personalized diet intervention cut BMI by 33% and reduced biological age by 8 years in morbidly obese patients.
Diabetes drugs like empagliflozin show surprising anti-aging effects โ mimicking caloric restriction and reducing senescent cell burden.
New research reveals how mitochondrial metabolism regulates dendritic cells' ability to activate anti-tumor immunity.
Large NHANES study reveals metabolic syndrome causes measurable acceleration in epigenetic aging clocks, offering new targets for intervention.
Research reveals how the steroid hormone pregnenolone allows cancer cells to evade immune detection and reduces immunotherapy effectiveness.
Mice lacking the HDAC9 gene gained less fat with age, accumulated fewer senescent cells, and showed improved mitochondrial respiration in adipose tissue.
Scientists identify how different immune cells use specific nutrient transporters, revealing new targets for autoimmune diseases.
New research reveals how specific gene combinations affect how quickly pre-diabetes advances to full type 1 diabetes.
Multi-omic analysis reveals GLP-1 receptor agonists counter aging processes across multiple organ systems and biological pathways.
Researchers analyzed 2,911 proteins in 50,506 people to create a frailty score that predicts disease risk and biological aging.
Daily anthocyanin supplementation helped over half of prediabetic participants return to normal glucose tolerance in just 12 weeks.
Blocking mTOR forces cancer cells to rewire cholesterol uptake and transport, revealing new drug targets when combined with rapamycin.
NIH study identifies metabolic mechanism behind controversial skin condition and demonstrates successful treatment with mitochondrial complex I inhibitors.
New cryo-EM structures reveal how LYCHOS protein senses cholesterol levels to regulate mTORC1 signaling, offering drug targets for aging.
New research shows dietary methionine enhances kidney function to clear harmful inflammatory molecules from the bloodstream.
A newly identified mechanism shows how omega-3 fatty acids protect aging kidneys โ and why low FFAR4 receptor expression accelerates kidney disease.
A dual-action therapy combining a glucose-responsive hydrogel with stem cell exosomes dramatically speeds diabetic wound closure in mice.
Researchers found a dual-target approach that selectively destroys the most treatment-resistant form of acute myeloid leukemia.