Brain Inflammation Emerges as Key Target for Alzheimer's Prevention and Treatment
New research reveals how targeting brain inflammation could unlock novel therapeutic approaches for Alzheimer's disease.
20 articles
New research reveals how targeting brain inflammation could unlock novel therapeutic approaches for Alzheimer's disease.
IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.
A comprehensive review examines how marine-derived bioactives like omega-3s, astaxanthin, and polysaccharides may combat chronic neuroinflammation underlying major neurodegenerative diseases.
A comprehensive review reveals how immunosenescence and chronic neuroinflammation create a self-reinforcing cycle that accelerates dopaminergic neuron loss in Parkinson's disease.
Cerebral hypoperfusion drives glymphatic dysfunction in systemic inflammation โ and restoring blood flow with levosimendan reverses it.
Scientists discover three distinct immune cell types guarding the brain's choroid plexus, opening new therapeutic pathways.
New research reveals how ubiquitin ligase COP1 suppresses brain inflammation by degrading c/EBPฮฒ protein in microglia cells.
New mouse study reveals aging causes region-specific neuroinflammation and perineuronal net accumulation linked to memory decline.
Scientists uncover the molecular mechanisms driving microglial aging in the brain, offering insights into neurodegeneration.
Single-cell analysis reveals how the flavonoid fisetin may reduce neuroinflammation in Alzheimer's disease by targeting specific astrocyte subgroups.
AAV delivery of AIBP protein restores cholesterol balance, silences inflammation, and preserves vision in glaucoma models.
New research reveals combined treatments targeting multiple brain pathways outperform traditional single-drug strategies for Alzheimer's disease.
New research reveals that gene therapy for SMA causes significant immune activation, suggesting immune dysfunction is central to the disease.
Recent breakthrough drugs targeting amyloid plaques slow cognitive decline, but combination therapies may unlock better outcomes.
New review reveals how senescent brain cells fuel Alzheimer's progression and highlights promising senolytic therapies for cognitive protection.
A 9-day intranasal insulin regimen restored working memory, recognition memory, and reduced neuroinflammation in mice engineered to mimic hippocampal aging.
Researchers develop novel immunotherapy using modified brain cells to target Alzheimer's pathology directly in the brain.
New review reveals how engineered peptides could revolutionize Alzheimer's therapy by targeting multiple disease pathways simultaneously.
Researchers discover a phospholipid derivative that protects brain cells by calming overactive immune cells in dementia-prone mice.
A novel Aฮฒ1-10 peptide vaccine conjugated to carrier proteins reduced plaques, neuroinflammation, and memory deficits in an AD mouse model.