20 articles
A completed University of Michigan trial explored how aerobic exercise training alters RAGE-mediated inflammatory pathways in type 2 diabetic adults.
A completed trial investigates whether replenishing glutathione precursors can reverse metabolic dysfunction in elderly adults.
A completed Danish trial investigates how blocking IL-6 signaling with tocilizumab alters fat, glucose, and protein metabolism in humans.
Enanta Pharmaceuticals tests its FXR agonist EDP-305 in a completed Phase 2 randomized trial for non-alcoholic steatohepatitis.
Mediterranean diet, resistance training, and diabetes medication combined to combat sarcopenia and improve metabolic health in older adults.
Maastricht University investigated whether NA, NAM, and tryptophan together could restore mitochondrial function in physically compromised older adults.
275-patient study tests novel liver-targeted therapy for NASH, a serious form of fatty liver disease affecting millions worldwide.
Wake Forest study explores whether the diabetes drug metformin can trigger cellular changes linked to longevity in healthy people.
New study reveals metformin's anti-aging effects depend entirely on whether you're insulin resistant or sensitive.
Carmot Therapeutics tests CT-868, a novel dual incretin receptor agonist, for HbA1c reduction in overweight and obese adults with poorly controlled T2DM.
Major trial tests whether diabetes drug metformin can prevent frailty syndrome that affects millions of aging adults.
French study reveals how aging influences metabolic responses to cancer, potentially explaining malnutrition patterns in elderly patients.
Swiss researchers studied how mTOR protein in fat tissue affects metabolism and insulin function throughout the body.
Clinical trial tested whether metformin could improve surgical outcomes and reduce hospital stays in non-diabetic older patients.
176-person trial tested whether pioglitazone could improve liver health by targeting insulin resistance in patients with fatty liver disease.
A completed OSU trial investigates whether short-term exercise training can restore impaired mitochondrial cleanup pathways in overweight and obese skeletal muscle.
VA study tests whether combining lifestyle changes with metformin can reverse muscle loss and frailty in obese older adults.
Researchers mapped how anesthetics, nitric oxide, and other drugs alter hemoglobin's grip on oxygen — with real implications for critical care.
169-person study tests whether intermittent fasting and low-carb approaches can reverse insulin resistance and metabolic dysfunction.
Takeda's Phase 1 trial evaluates the safety and tolerability of TAK-510, a novel injectable agent targeting nausea and vomiting, across escalating doses.
