20 articles
A comprehensive review reveals how inflammaging—the fusion of aging and inflammation—fuels cardiovascular disease through senescence, mitochondrial dysfunction, and gut dysbiosis.
Mendelian randomization links circulating inflammatory proteins to retinal microvascular changes, heart disease risk, and lifespan — establishing causal direction.
Researchers created synthetic immune receptors that boost macrophages' ability to clear cellular debris, reducing inflammation in liver and heart disease.
German study explored how lifelong inflammatory burden contributes to cardiac aging by measuring heart rate variability changes.
New research reveals how modulating immune cells in arterial plaques could reduce cardiovascular disease progression.
Novel liposome therapy delivers miR-10a to atherosclerotic plaques, reprogramming inflammatory macrophages and reducing disease progression in mice.
Dive deep into the molecular mechanisms of vascular aging and explore cutting-edge interventions — from senolytic therapies and nitric oxide restoration to exercise-induced remodeling and emerging pharmacological approaches — that are redefining what's possible in cardiovascular longevity.
A 2025 review maps the molecular mechanisms driving cardiovascular aging—from inflammaging to ECM remodeling—and outlines emerging therapies.
A new review examines how drugs that clear senescent cells could transform treatment of age-related cardiovascular disease.
Advanced spatial mapping shows vascular regions drive cardiac aging through inflammation and senescence accumulation.
Isolinderalactone from Lindera aggregata root reduces atherosclerotic plaques by targeting key inflammatory pathways in immune cells.
A 2025 review maps the molecular drivers of cardiac aging and evaluates drugs, CRISPR, stem cells, and lifestyle as countermeasures.
A landmark Circulation review reveals how aging blood vessels accelerate systemic decline — and outlines emerging therapies to stop it.
Researchers outline promising therapies for Takayasu arteritis that could reduce cardiovascular complications in young women.
A 2-year clinical trial testing Juice Plus+ products against low-grade inflammation and biological aging markers in overweight seniors was terminated before completion.
New paradigm targets inflammation and neurohormonal dysfunction to achieve heart failure remission rather than just symptom management.
Cardiologist explains how chronic inflammation damages arteries and triggers blood clots before cholesterol becomes problematic.
In obese middle-aged mice, reducing dietary protein—without cutting calories—reversed cardiac inflammation and remodeling via AMPK-ULK1 mitophagy.
TREM-1 inhibitor LR12 reduced harmful plaque formation in stents by nearly 50% without affecting healing in rabbit studies.
Scientists discover how a molecular switch in blood vessel cells accelerates aging and plaque formation, revealing new therapeutic targets.
