Brain Health
Brain Inflammation Emerges as Key Target for Alzheimer's Prevention and Treatment
New research reveals how targeting brain inflammation could unlock novel therapeutic approaches for Alzheimer's disease.
Research Paper
Mar 28, 2026 2
Results for "Inflammaging Therapeutics" in Parkinson's
20 articles
Brain Health
New Brain Mapping Tool Reveals Lymphocytes Drive Inflammation in Brain Aging
IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.
Research Paper
May 13, 2026 0
Brain Health
Marine Compounds Show Promise Against Neuroinflammation Driving Alzheimer's and Parkinson's
A comprehensive review examines how marine-derived bioactives like omega-3s, astaxanthin, and polysaccharides may combat chronic neuroinflammation underlying major neurodegenerative diseases.
Research Paper
May 3, 2026 0
Brain Health
Arthritis Drug Eases Treatment-Resistant Depression by Calming Inflammation
A small trial found tocilizumab, an anti-inflammatory drug, cut depression remission rates better than SSRIs by targeting IL-6, not brain chemistry.
Press Release
May 28, 2026 0
Brain Health
How Immune Aging Drives Parkinson's Disease and What We Can Do About It
A comprehensive review reveals how immunosenescence and chronic neuroinflammation create a self-reinforcing cycle that accelerates dopaminergic neuron loss in Parkinson's disease.
Research Paper
Jun 12, 2026 0
Brain Health
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Neuroendocrine Longevity: Advanced Mechanisms of Hypothalamic Aging and Therapeutic Targeting
A deep mechanistic exploration of how hypothalamic IKKฮฒ/NF-ฮบB signaling, htNSC exosomal communication, and multi-axis hormonal dysregulation drive systemic aging โ plus cutting-edge therapeutic strategies.
TutorialAdvanced
May 28, 2026 0
Brain Health
Boosting Brain Blood Flow Rescues the Brain's Waste-Clearance System During Sepsis
Cerebral hypoperfusion drives glymphatic dysfunction in systemic inflammation โ and restoring blood flow with levosimendan reverses it.
Research Paper
May 14, 2026 0
Brain Health
Brain Barrier Immune Cells Reveal New Targets for Neuroinflammation Treatment
Scientists discover three distinct immune cell types guarding the brain's choroid plexus, opening new therapeutic pathways.
Research Paper
Mar 29, 2026 1
Brain Health
Brain Protein COP1 Controls Neuroinflammation by Targeting Key Inflammatory Factor
New research reveals how ubiquitin ligase COP1 suppresses brain inflammation by degrading c/EBPฮฒ protein in microglia cells.
Research Paper
Apr 10, 2026 0
Brain Health
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The Hypothalamus as a Longevity Hub: Molecular Mechanisms of Neuroendocrine Aging
Go beneath the surface to explore how NF-ฮบB signaling, IKKฮฒ activation, and hypothalamic stem cell decline drive whole-body aging โ and which interventions can slow the process.
TutorialIntermediate
May 27, 2026 0
Brain Health
USC Scientists Find Brain Enzyme Behind Alzheimer's Inflammation and How to Block It
New compounds targeting the cPLA2 enzyme may reduce Alzheimer's-linked brain inflammation, especially in high-risk APOE4 gene carriers.
Press Release
May 26, 2026 0
Brain Health
NIA Research Roundup Highlights Dementia Risk, Calorie Restriction and Alzheimer's Genes
Recent NIA findings spotlight lifestyle factors cutting Alzheimer's risk by 60%, calorie restriction slowing aging, and a gene regulating plaque toxicity.
Press Release
Apr 21, 2026 0
Brain Health
Aging Brain Builds PNN Armor in Hippocampus While Striatum Stays Inflamed
New mouse study reveals aging causes region-specific neuroinflammation and perineuronal net accumulation linked to memory decline.
Research Paper
May 16, 2026 0
Brain Health
New Research Reveals How Brain Immune Cells Age at the Subcellular Level
Scientists uncover the molecular mechanisms driving microglial aging in the brain, offering insights into neurodegeneration.
Research Paper
Apr 2, 2026 0
Brain Health
Fisetin Targets Brain Inflammation in Alzheimer's Through CD44 Protein Pathway
Single-cell analysis reveals how the flavonoid fisetin may reduce neuroinflammation in Alzheimer's disease by targeting specific astrocyte subgroups.
Research Paper
Apr 2, 2026 0
Brain Health
Single Gene Injection Shields Retinal Cells From Glaucoma Damage
AAV delivery of AIBP protein restores cholesterol balance, silences inflammation, and preserves vision in glaucoma models.
Research Paper
Jun 22, 2026 0
Brain Health
Multi-Target Alzheimer's Therapy Shows Promise Over Single-Drug Approaches
New research reveals combined treatments targeting multiple brain pathways outperform traditional single-drug strategies for Alzheimer's disease.
Research Paper
Mar 28, 2026 2
Brain Health
Gene Therapy for Spinal Muscular Atrophy Triggers Unexpected Immune Inflammation
New research reveals that gene therapy for SMA causes significant immune activation, suggesting immune dysfunction is central to the disease.
Research Paper
Apr 17, 2026 0
Brain Health
New Alzheimer's Drugs Show Promise But Multimodal Approaches May Be Key
Recent breakthrough drugs targeting amyloid plaques slow cognitive decline, but combination therapies may unlock better outcomes.
Research Paper
Mar 28, 2026 2
Brain Health
Cellular Senescence Drives Alzheimer's Disease and Brain Aging
New review reveals how senescent brain cells fuel Alzheimer's progression and highlights promising senolytic therapies for cognitive protection.
Research Paper
Apr 2, 2026 0
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