20 articles
Advanced biological macromolecules show promise for regenerating damaged joints and reducing inflammation in rheumatoid arthritis.
Master the cutting-edge molecular targets, clinical trial data, and emerging therapeutic strategies aimed at reversing ECM aging โ from senolytic combinations to biomaterial scaffolds and epigenetic reprogramming.
A novel photoactivatable drug system uses NK immune cells to eliminate aging joint cells, reducing osteoarthritis progression in mice.
New review reveals how plant-based compounds and stem cell therapies could eliminate aging cells and restore youthful function.
Novel nanoparticle therapy converts inflammatory macrophages into healing cells that deliver healthy mitochondria to damaged spinal discs.
Go beyond the basics to understand the enzymes, signaling pathways, and cellular crosstalk that govern how your extracellular matrix ages โ and what researchers are doing about it.
New research reveals how extracellular vesicles can both accelerate aging and potentially reverse it through targeted therapy.
Researchers found a way to restore aging stem cells' healing power, potentially improving treatments for immune diseases.
A sweeping review maps every known strategy for delivering therapies directly to mitochondria, from lifestyle habits to nanocarriers and gene editing.
New research reveals how heart attacks trigger cascading damage and identifies promising combination therapies to protect the heart.
New research reveals how immune cells interact with liver scarring processes, opening doors to innovative treatments.
New technique combines your own cells with light therapy to supercharge mitochondria for dramatic skin regeneration and wound healing.
New regenerative approaches using stem cells and biostimulatory compounds promise to restore skin function by targeting root causes of aging.
A novel anti-swelling hydrogel loaded with dasatinib, quercetin, and nucleus pulposus exosomes clears senescent cells and restores disc integrity in rats and goats.
Single-cell sequencing reveals ferroptosis drives pulpitis; thymosin ฮฑ1 restores GPX4, cuts iron overload, and reduces inflammation in cells and rats.
Novel nanogel therapy targets mitochondrial ROS to break the inflammation-hypoxia cycle in periodontitis, showing strong preclinical results.
ProcyanidinC1, a natural senolytic, selectively eliminates senescent cells in diabetic skin, dramatically improving wound healing in mouse models.
A microRNA reduced by mechanical stress may hold both diagnostic and therapeutic promise for osteoarthritis in knee and jaw joints.
Discover how revolutionary drugs target 'zombie cells' that accumulate with age, potentially reversing aging and extending healthspan.
A landmark review reveals the molecular pathways driving thymic self-repair after injury, with major implications for aging immunity.
