20 articles
New research reveals how chronic inflammation varies by person, paving the way for personalized interventions to combat age-related diseases.
A comprehensive review reveals how inflammaging—the fusion of aging and inflammation—fuels cardiovascular disease through senescence, mitochondrial dysfunction, and gut dysbiosis.
New research reveals how low-grade inflammation creates a cycle of liver damage in older adults, pointing to promising therapeutic targets.
A major cross-population study finds that chronic inflammation linked to aging may reflect industrialized lifestyles, not biology alone.
New therapies targeting inflammation pathways could reduce cardiovascular disease and slow kidney disease progression in CKD patients.
Mendelian randomization links circulating inflammatory proteins to retinal microvascular changes, heart disease risk, and lifespan — establishing causal direction.
A landmark 2025 review maps the molecular and cellular mechanisms driving immune aging, linking inflammaging to cancer, neurodegeneration, and infection.
Revolutionary framework combines quarterly biomarker testing with AI-powered lifestyle coaching to reduce aging-related inflammation.
New research maps the connection between cellular senescence, chronic inflammation, and cardiovascular disease progression.
Researchers identify how immune cell cleanup failures drive heart disease and develop targeted therapies to restore vascular health.
New research reveals kidneys actively fuel systemic inflammation during aging, offering targets for longevity interventions.
Advanced biological macromolecules show promise for regenerating damaged joints and reducing inflammation in rheumatoid arthritis.
New research reveals how targeting brain inflammation could unlock novel therapeutic approaches for Alzheimer's disease.
Researchers discover how glucocorticoids, metformin, and dimethyl fumarate work by targeting immune cell metabolism pathways.
New review maps the glial cell pathways linking chronic neuroinflammation to Alzheimer's, Parkinson's, and ALS — and ranks drugs that may help.
New research reveals how immune aging creates systemic inflammation that accelerates kidney disease, autoimmune conditions, and other age-related illnesses.
New research reveals how tissue fibroblasts orchestrate age-related inflammation, creating exhausted T cells that increase vulnerability to disease.
Researchers identify specific inflammatory kidney cells that could be targeted with existing drugs to slow chronic kidney disease progression.
Research from sub-Saharan Africa shows urbanization dramatically alters inflammaging patterns, challenging universal aging models.
A major review reveals how inflammaging and immunosenescence synergistically drive colorectal cancer in older adults, reshaping the tumor microenvironment.
