Klotho Protein Counters 8 of 12 Major Aging Hallmarks in Comprehensive Review
New analysis reveals how the antiaging protein Klotho protects against inflammation, cellular damage, and organ dysfunction across multiple aging pathways.
20 articles
New analysis reveals how the antiaging protein Klotho protects against inflammation, cellular damage, and organ dysfunction across multiple aging pathways.
Review reveals how αKlotho protein controls mineral metabolism and offers therapeutic potential for age-related diseases.
New review reveals how declining Klotho levels drive insulin resistance and type 2 diabetes, positioning this anti-aging protein as a potential biomarker.
Review reveals how Klotho protein protects against periodontitis, oral cancer, and other mouth diseases through multiple cellular pathways.
A new joint venture completes a key manufacturing step for a cell therapy designed to restore α-Klotho, a protein linked to aging and disease.
New research explores how the longevity protein Klotho could revolutionize periodontitis diagnosis and treatment approaches.
New research reveals how the anti-aging protein klotho prevents harmful calcium buildup in brain structures during aging.
New research explores using Klotho protein with stem cell-derived vesicles to treat acute kidney injury, potentially offering regenerative therapy.
A muscle-secreted protein boosted by exercise declines with age — restoring it in old mice reverses muscle weakness and bone loss.
A new wave of biotechs is targeting aging as a root cause, using encapsulated cells and gene therapy to restore lost proteins and reverse decline.
Ganoderma lucidum spore powder extended lifespan and increased α-Klotho levels across organs in worms and mice aging models.
Scientists show how the Alzheimer's risk gene CLU protects synapses by dampening astrocyte inflammation and microglial pruning activity.
A newly identified protein in blood vessel walls slows vascular aging in mice — and gene therapy targeting it shows promising results.
A key metabolic ratio tied to inflammation and aging may reverse multiple age-related biological changes — here's what the science shows.
New research reveals how a protein-sensing gut hormone directs dietary preferences and impacts longevity through conserved mechanisms.
A large UK Biobank proteomics study pinpoints 134 plasma proteins tied to osteoporosis, with a 10-protein model predicting onset up to 5 years ahead.
Scientists boosted a protein that dampens chronic inflammation, and older mice grew stronger, more energetic, and had healthier bones.
A liver-specific protein triggers aging not through cell death, but by spreading senescence via mitochondrial dysfunction and inflammatory signals.
A first-of-its-kind proteomics study finds acute cold exposure shifts 185 circulating proteins in a cardioprotective, anti-aging direction across independent cohorts.
The circadian CLOCK protein plays a dual role in cellular senescence — supporting healthy aging in normal cells while enabling tumor growth when hijacked.