20 articles
New research reveals how KLF2 and KLF3 proteins regulate T cell movement and exhaustion, offering insights for immune system optimization.
A new in vitro study shows Thymosin α1 triggers dendritic cells to release IL-15, boosting CD8+ T cell killing and reducing HIV reservoir size.
Mice lacking the PERP apoptosis gene develop faulty thymic immune screening, accumulating self-reactive T-cells that trigger arthritis as they age.
New research reveals how RNA-binding proteins orchestrate immune responses, offering insights into preventing chronic inflammation.
New research reveals how SIRT2 regulates T cell responses, potentially improving cancer immunotherapy and immune function.
New research reveals how our body clock regulates immune cell function through DNA modifications, offering insights for health optimization.
Senescent cells drive cyst growth in ADPKD, and targeting them with senolytics or the aldose reductase inhibitor epalrestat delays disease progression.
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
New research reveals how removing ZFP148 protein boosts CD8+ T cells' cancer-fighting ability and improves immunotherapy response.
Researchers identify how TSLP protein creates regulatory T cells that suppress immune responses in melanoma.
New research reveals how albumin, a common blood protein, may protect against life-threatening fungal infections.
Researchers identify protein stress as key factor limiting natural killer cell survival in cancer treatment.
A 2025 meta-analysis of 11 RCTs finds Tα1 reduces 28-day sepsis mortality overall, but high-quality trial data tells a more nuanced story.
New research reveals how necroptosis activates immune pathways, offering targets for inflammatory bowel disease treatment.
Stanford researchers used modified immune proteins to enhance neurogenesis and cognitive function in aged mouse brains.
A new review reveals how diet, exercise, and stress reduction can measurably reverse key markers of immune aging and inflammaging.
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
Phase 2 trial tests novel therapy for patients who failed standard biologics and JAK inhibitors in 145-person study.
New research reveals how IL-2 signaling generates special B cells that produce anti-inflammatory compounds, potentially slowing aging processes.
Master the molecular architecture of complement dysregulation in aging — from regulatory protein biochemistry to cutting-edge therapeutic targets — and understand how precision interventions can restore balance without dismantling immunity.
