Cancer Research
KLHL6 Protein Prevents T Cell Exhaustion and Boosts Cancer Immunity
Scientists discover KLHL6 protein prevents immune cell dysfunction in tumors, offering new target for cancer immunotherapy.
Research Paper
Apr 9, 2026 0
Results for "Klotho Protein" in Cancer
20 articles
Cancer Research
Protein Quality Control Holds the Key to Supercharging Cancer-Fighting T Cells
Scientists discover that maintaining proteostasis in tumor-infiltrating lymphocytes prevents exhaustion and boosts immunotherapy outcomes.
Research Paper
May 1, 2026 0
Cancer Research
DNA Therapy Slashes Bad Cholesterol by 50% Without Statin Side Effects
A new DNA-based treatment blocks the PCSK9 protein, cutting LDL cholesterol by nearly 50% while avoiding common statin side effects.
Press Release
May 2, 2026 0
Cancer Research
Urine Test May Soon Track Senescent Cells in Cancer and Fibrosis
Cambridge scientists engineer a nanoprobe that detects therapy-induced senescence non-invasively through a simple urine colorimetric test.
Research Paper
May 14, 2026 0
Cancer Research
LARP4 Protein Drives T Cell Exhaustion in Cancer Through Mitochondrial Dysfunction
New research reveals how LARP4 protein causes T cells to malfunction in tumors by disrupting cellular energy production.
Research Paper
Apr 2, 2026 0
Cancer Research
mRNA Tail Sequences Act as Protein Chaperones to Prevent Misfolding
Scientists discover that 3' UTRs of mRNAs actively guide protein folding during translation, controlling activity of key cancer and aging regulators.
Research Paper
Jun 11, 2026 0
Cancer Research
P53 Protein Controls Tumor Growth Through Oxygen-Sensing Mechanism
New research reveals how the p53 tumor suppressor protein fights cancer by activating cell death pathways when oxygen levels drop.
Research Paper
Mar 29, 2026 1
Cancer Research
Hidden Protein Shields Liver Cancer Cells From a Key Cell Death Pathway
Scientists uncover how SCRN1 blocks ferroptosis in liver cancer, revealing new targets for treating drug-resistant hepatocellular carcinoma.
Research Paper
May 22, 2026 0
Cancer Research
Scientists Discover CDK10 Protein That Helps Cancer Hide From Immune System
Researchers identify a key protein that suppresses immune responses against tumors, opening new paths for cancer immunotherapy.
Research Paper
Mar 29, 2026 1
Cancer Research
Cancer Protein OASL Hijacks Cell Machinery to Fuel Tumor Growth Through Fat Production
New research reveals how a cancer-promoting protein reprograms cellular fat production to accelerate tumor progression.
Research Paper
Apr 4, 2026 0
Cancer Research
Liver Protein ATF6α Drives Cancer Growth by Blocking Immune System Detection
New research reveals how a liver protein helps tumors evade immune surveillance, opening doors for targeted cancer therapies.
Research Paper
Mar 28, 2026 0
Cancer Research
5-Oxoproline Prevents Doxorubicin Heart Damage While Fighting Cancer
Metabolite supplement protects heart from chemo toxicity and enhances tumor suppression in breakthrough dual-action study.
Research Paper
Apr 3, 2026 0
Cancer Research
Strength Training Fights Inflammaging in Bone Marrow Transplant Survivors
A 10-week supervised strength program targets chronic inflammation and self-efficacy in long-term allogeneic HCT survivors.
Clinical Trial
May 25, 2026 0
Cancer Research
Galectin-9 Emerges as New Target for Chronic Lymphocytic Leukemia Immunotherapy
Multi-omics study reveals exhausted T-cells in CLL lymph nodes and identifies galectin-9 as a promising therapeutic target for overcoming immune evasion.
Research Paper
Mar 27, 2026 13
Cancer Research
Alpha-Ketoglutarate Controls Cancer Cell Energy Sensing Through AMPK Protein
New research reveals how α-ketoglutarate regulates AMPK synthesis, offering potential cancer therapy targets through energy stress.
Research Paper
Apr 3, 2026 0
Cancer Research
Tumor Cholesterol Blocks PD-L1 Destruction to Escape Immune Attack
Cancer cells exploit cholesterol biosynthesis to keep PD-L1 high, silencing T cells — and blocking this pathway restores anti-tumor immunity.
Research Paper
May 22, 2026 0
Cancer Research
Single Protein Knockout Keeps Cancer-Fighting CAR T Cells Alive Longer
Disabling the NFIL3 protein prevents CAR T cell exhaustion, boosting tumor-fighting power in animal models of hard-to-treat cancers.
Press Release
Jun 3, 2026 0
Cancer Research
Boosting Cellular Cleanup Systems Could Supercharge Cancer-Fighting T Cells
Scientists discover that enhancing protein cleanup in immune cells prevents exhaustion and dramatically improves cancer immunity.
Research Paper
Mar 28, 2026 1
Cancer Research
New Kinase Target STK40 Cracks Open Liver Cancer Immune Resistance
A CRISPR screen reveals STK40 suppresses anti-tumor immunity in liver cancer — blocking it supercharges immunotherapy response.
Research Paper
May 30, 2026 0
Cancer Research
Blocking PID1 Reprograms Tumor Macrophages to Fight Cancer via Oxysterols
Targeting a single protein in immune cells rewires cholesterol metabolism to flip immunosuppressive macrophages into tumor-fighting ones.
Research Paper
Jun 23, 2026 0
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