20 articles
New cryo-EM structures reveal how LYCHOS protein senses cholesterol levels to regulate mTORC1 signaling, offering drug targets for aging.
Researchers analyzed 2,911 proteins in 50,506 people to create a frailty score that predicts disease risk and biological aging.
Flavo-Proxylane topical treatment plus ultrasound reduced skin laxity by 44% in people using weight loss medications.
A newly identified protein shields the liver from alcohol injury by bridging mitochondria and fat droplets to enhance fatty acid oxidation.
A newly identified mitochondrial NAD transporter in fat cells controls whether you develop obesity and insulin resistance as you age.
Large study reveals specific blood proteins can identify who will die from heart disease a decade before death occurs.
New research reveals how a key cellular protein prevents ferroptosis, a type of cell death implicated in aging and age-related diseases.
A newly identified mechanism shows how omega-3 fatty acids protect aging kidneys — and why low FFAR4 receptor expression accelerates kidney disease.
Scientists discover how a hypothalamic calcium channel detects leucine from dietary protein to trigger satiety and drive weight loss.
Mice lacking the HDAC9 gene gained less fat with age, accumulated fewer senescent cells, and showed improved mitochondrial respiration in adipose tissue.
Major study of 255,000+ people shows optimal cardiovascular health dramatically reduces disease progression and mortality risk.
A 6-month AI-driven personalized diet intervention cut BMI by 33% and reduced biological age by 8 years in morbidly obese patients.
New research reveals how RAP1A protein regulates liver blood vessel function and may influence fibrosis progression in chronic liver disease.
New JAMA research suggests reducing dietary protein may slow kidney disease progression and improve patient outcomes.
A noninvasive 13-variable score reveals how fast your liver is aging — and accelerated liver aging raises mortality risk by up to 85%.
Multi-omic analysis reveals GLP-1 receptor agonists counter aging processes across multiple organ systems and biological pathways.
Large-scale study identifies three key blood proteins that predict diabetic retinopathy development with 90% accuracy.
Researchers discover unique molecular patterns in lipedema patients and develop predictive models for this poorly understood condition affecting women.
New England Journal review explores the expanding therapeutic potential of GLP-1 drugs beyond diabetes treatment.
Large-scale protein analysis enhanced diabetes risk prediction by 23-29%, offering new tools for early prevention strategies.
