Fat-Regulating Protein HSL Has a Hidden Role That Rewrites Obesity Science
A key fat metabolism protein works inside cell nuclei to keep fat tissue healthy — its absence causes fat loss, not gain.
20 articles
A key fat metabolism protein works inside cell nuclei to keep fat tissue healthy — its absence causes fat loss, not gain.
A methionine-supplemented longevity diet outperformed Western and ketogenic diets by reducing frailty, fat mass, and insulin resistance while elevating GH, GLP-1, and FGF21.
A protein thought only to burn fat secretly protects fat cell health from inside the nucleus, reshaping obesity and metabolic disease research.
Meta-analysis of 17 trials reveals leucine's role in maintaining strength and muscle function as we age, even without mass gains.
A large NHANES cohort study finds that higher serum micronutrient levels reduce all-cause mortality partly by decelerating biological aging.
Reducing protein to recommended levels may double the longevity hormone FGF21, improving fat loss and insulin sensitivity within weeks.
Small study reveals how exercise plus protein intake triggers beneficial gene changes in older women at metabolic risk.
Dr. Valter Longo challenges the peptide and GLP-1 boom, arguing the full body of evidence points toward fasting, plant protein, and lower IGF-1.
New research reveals thyroglobulin levels can help assess iodine deficiency in pregnant women, linking maternal nutrition to birth outcomes.
Study reveals oxytocin hormone changes during ketogenic dieting may predict weight loss success and ketosis achievement.
New muscle biopsy research reveals how 15g collagen activates insulin pathways and resets mitochondrial function beyond joint health.
Dr. Chris McGlory reveals how 5g daily omega-3 supplementation could help preserve muscle mass and strength in aging adults.
Go beyond antioxidant basics to explore how polyphenols hijack transcription factor networks, remodel chromatin, and what randomized trials actually show about aging biomarkers.
New research reveals how fecal transplants from 100-year-olds may slow aging, while your own microbiome can help maintain weight loss.
Milk protein lactoferrin protects against radiation-induced gut injury by promoting cellular cleanup and reducing inflammation.
New research shows plant-based proteins promote healthier gut microbiomes and lower body weight compared to animal proteins in seniors.
FGF21 extends lifespan in animals by 30-40%. Here's what exercise and diet research reveals about boosting it naturally.
Hair graying and skin aging are metabolic problems driven by declining NAD+ levels, not just structural changes.
New systematic review finds dietary protein intake doesn't accelerate kidney decline in adults 65+, challenging restrictive recommendations.
A Mass General Brigham trial found multivitamin users aged slower on 5 epigenetic clocks, with the biggest gains in those aging fastest.