20 articles
A new joint venture completes a key manufacturing step for a cell therapy designed to restore α-Klotho, a protein linked to aging and disease.
A new wave of biotechs is targeting aging as a root cause, using encapsulated cells and gene therapy to restore lost proteins and reverse decline.
Scientists boosted a protein that dampens chronic inflammation, and older mice grew stronger, more energetic, and had healthier bones.
New research reveals how a key dermal protein controls fast-cycling skin cells that maintain youthful skin integrity.
New genetic and proteomic findings from centenarian studies uncover biological markers that distinguish the longest-lived humans from the rest of us.
New research identifies FTL1 protein as key driver of brain aging. Reducing it restored memory and neural connections in mice.
A Japanese study of 495 centenarians finds elevated NfL blood levels strongly linked to worse cognition and 36% higher mortality risk.
Cyclarity's UDP-003 shows first human evidence of excreting oxidized cholesterol, pointing toward reversing arterial damage rather than just slowing it.
An $80M renewal of the Long Life Family Study uncovers genes, proteins, and fitness traits that predict exceptional longevity.
Scientists identify a primate-specific long non-coding RNA that accelerates cellular aging, opening new targets for senescence intervention.
A newly identified protein in yeast and humans helps degrade toxic alpha-synuclein, offering a fresh target for Parkinson's therapy.
A key fat metabolism protein works inside cell nuclei to keep fat tissue healthy — its absence causes fat loss, not gain.
New research reveals how declining Pck1 enzyme levels cause fat cells to age faster, potentially explaining age-related metabolic decline.
New research reveals omega-3s activate a receptor that curbs cellular senescence and fibrosis in kidneys, pointing to a clear biological mechanism.
Scientists discovered hundreds of unknown mini-proteins in failing hearts, potentially reshaping how we understand disease at the cellular level.
Lysoway's LW-1017 aims to restore lysosomal function in aging brains, potentially slowing Alzheimer's before toxic proteins accumulate.
Sam Altman-backed Retro Biosciences enters clinical trials with a drug targeting Alzheimer's protein clumps, aiming to add 10 healthy years to human life.
A neuron-specific protein disposal mechanism may explain why normal tau protein clumps in sporadic Alzheimer's disease, new research reveals.
Scientists identify RORA and prion protein as key drivers of age-related cataracts, opening doors to targeted non-surgical treatments.
Kenny Wilson's research identifies a gene that helps neurons transport proteins more efficiently, potentially protecting against Alzheimer's disease.
