Klotho Protein Counters 8 of 12 Major Aging Hallmarks in Comprehensive Review
New analysis reveals how the antiaging protein Klotho protects against inflammation, cellular damage, and organ dysfunction across multiple aging pathways.
20 articles
New analysis reveals how the antiaging protein Klotho protects against inflammation, cellular damage, and organ dysfunction across multiple aging pathways.
Review reveals how αKlotho protein controls mineral metabolism and offers therapeutic potential for age-related diseases.
New research reveals how the longevity protein Klotho may protect against Alzheimer's disease, with Mediterranean diet potentially boosting levels.
New review reveals how declining Klotho levels drive insulin resistance and type 2 diabetes, positioning this anti-aging protein as a potential biomarker.
Review reveals how Klotho protein protects against periodontitis, oral cancer, and other mouth diseases through multiple cellular pathways.
New research explores how the longevity protein Klotho could revolutionize periodontitis diagnosis and treatment approaches.
New research reveals how the anti-aging protein klotho prevents harmful calcium buildup in brain structures during aging.
New research explores using Klotho protein with stem cell-derived vesicles to treat acute kidney injury, potentially offering regenerative therapy.
A muscle-secreted protein boosted by exercise declines with age — restoring it in old mice reverses muscle weakness and bone loss.
Ganoderma lucidum spore powder extended lifespan and increased α-Klotho levels across organs in worms and mice aging models.
Scientists show how the Alzheimer's risk gene CLU protects synapses by dampening astrocyte inflammation and microglial pruning activity.
New research reveals how a protein-sensing gut hormone directs dietary preferences and impacts longevity through conserved mechanisms.
A large UK Biobank proteomics study pinpoints 134 plasma proteins tied to osteoporosis, with a 10-protein model predicting onset up to 5 years ahead.
A liver-specific protein triggers aging not through cell death, but by spreading senescence via mitochondrial dysfunction and inflammatory signals.
New research reveals how a key brain protein regulates stress hormones, body temperature, and fat storage in adults.
Large UK Biobank study identifies 227 aging-related proteins and discovers non-linear aging patterns with distinct biological shifts.
UK Biobank analysis of 2,920 proteins in 48,728 people identifies 71 key aging biomarkers and potential drug targets.
A UK Biobank proteomics study of 24,920 people identifies 60 proteins tied to metabolic aging and discovers wave-like protein surges at key ages.
Scientists discover how a protein causing rapid aging in rare disease also drives normal aging in healthy people.
New research identifies YTHDF1 as a key factor that determines how mTORC1 signaling contributes to various aging processes.