20 articles
Study of 2,366 women shows biological aging markers predict future increases in tau, amyloid, and neuroinflammation proteins linked to dementia.
Three-decade study tracks MS prevalence, lifestyle factors, and mortality patterns in England, revealing important health trends.
A 38-year Finnish cohort study finds higher lifelong physical activity protects information processing and working memory into midlife.
Researchers combined ultrasound with gene therapy to treat Leigh syndrome, significantly extending survival in mouse models.
New research identifies WDR12 and HIVEP3 genes as key contributors to exceptional cognitive preservation in elderly Amish individuals.
New research reveals how the longevity protein Klotho may protect against Alzheimer's disease, with Mediterranean diet potentially boosting levels.
Prolonged sleep duration and later wake times predict faster cognitive decline, especially in older adults with amyloid and tau buildup.
New analysis reveals critical flaws in how we design studies to prevent cognitive decline and dementia.
A meta-analysis of 684,493 patients finds just 49% persist with anti-dementia drugs at 12 months, with major variation by drug type and study methodology.
DNA methylation biomarkers from a simple blood test may track cognitive aging and neurological disease risk with unprecedented precision.
OSK gene therapy targeting engram neurons restored memory to youthful levels in aged mice and Alzheimer's models, reversing senescence hallmarks.
Large trial of 513 older adults finds exercise and intensive cardiovascular risk reduction don't significantly improve cognitive function.
A multi-cohort study finds that every 5 km closer to a lead-releasing facility is tied to measurably lower episodic memory scores.
New study reveals how the locus coeruleus, a tiny brainstem region, affects cognitive practice effects in aging.
Researchers propose redesigning memory clinic services to match patient complexity with the right level of specialist oversight.
Following Mediterranean or MIND diets for decades significantly reduced dementia risk and slowed cognitive aging in 130,000+ adults.
New research reveals APOE2, the longevity-linked gene variant, shields human neurons from aging damage through enhanced DNA repair — not just lipid metabolism.
New research links age at Parkinson's onset and family history to the likelihood of carrying disease-causing genetic variants.
Breakthrough antisense therapy demonstrates sustained benefits for rare genetic form of ALS in extended clinical trial.
Study of 833 people finds depression linked to premature biological aging in both brain structure and DNA methylation patterns.
