Engineered T Cells Show Promise Against Deadly Mesothelioma Cancer
Small trial tests modified immune cells injected directly into chest cavity to fight aggressive cancer with 12-month survival rate.
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Small trial tests modified immune cells injected directly into chest cavity to fight aggressive cancer with 12-month survival rate.
Genetically modified immune cells target blood cancer that stopped responding to standard treatments in 28-patient trial.
A first-in-human trial shows CAR-modified stem cell memory T cells outperform standard CAR T cells in expansion, persistence, and complete responses.
Scientists develop innovative immunotherapy that reprograms multiple immune cell types to attack cancer while reducing side effects.
Engineered immune cells target harmful macrophages in tumors, transforming the cancer environment to boost natural anti-tumor immunity.
Scientists develop CAR T cells that attack tumor-supporting immune cells, showing promise for treating hard-to-target solid cancers.
Chinese researchers developed a breakthrough method to mass-produce powerful immune cells that hunt and destroy cancer tumors.
Scientists modified patients' immune cells to better recognize and attack cancer tumors expressing NY-ESO-1 protein.
A 10-week supervised strength program targets chronic inflammation and self-efficacy in long-term allogeneic HCT survivors.
A phase 1 trial shows Temferon โ a gene-engineered stem cell therapy โ safely delivers interferon-ฮฑ into glioblastoma tumors with no dose-limiting toxicities.
New 3-D spatial mapping reveals four distinct immune-evasion niches in osteosarcoma that explain why checkpoint therapies fail.
Autologous NK cell therapy combined with immunotherapy tested in 27 patients with treatment-resistant cancers.
New trial data reveals AstraZeneca's experimental in vivo CAR-T therapy showed early responses in multiple myeloma patients but resulted in one death.
Engineered immune cell vesicles first induce cancer cell senescence with chemo, then eliminate them with targeted senolytic drugs.
Researchers identify four LSC subtypes that predict venetoclax resistance and reveal matched subtype-specific therapies for AML patients.
BCG therapy for bladder cancer travels to bone marrow, reprogramming stem cells to produce enhanced immune cells that fight tumors throughout the body.
AML stem cells produce BHB via autonomous ketogenesis to block ferroptosis, revealing a targetable metabolic vulnerability in leukemia.
Engineered immune cells target liver cancer protein in phase I safety study, though trial ended early with 10 patients.
Modified immune cells engineered to overcome cancer's defenses completed safety testing in lymphoma patients.
Small trial tests innovative immune cell therapy for patients with relapsed non-Hodgkin's lymphoma who failed standard treatments.