Engineered T Cells Show Promise Against Deadly Mesothelioma Cancer
Small trial tests modified immune cells injected directly into chest cavity to fight aggressive cancer with 12-month survival rate.
20 articles
Small trial tests modified immune cells injected directly into chest cavity to fight aggressive cancer with 12-month survival rate.
Genetically modified immune cells target blood cancer that stopped responding to standard treatments in 28-patient trial.
Scientists modified patients' immune cells to better recognize and attack cancer tumors expressing NY-ESO-1 protein.
A 10-week supervised strength program targets chronic inflammation and self-efficacy in long-term allogeneic HCT survivors.
Autologous NK cell therapy combined with immunotherapy tested in 27 patients with treatment-resistant cancers.
Engineered immune cells target liver cancer protein in phase I safety study, though trial ended early with 10 patients.
Modified immune cells engineered to overcome cancer's defenses completed safety testing in lymphoma patients.
Small trial tests innovative immune cell therapy for patients with relapsed non-Hodgkin's lymphoma who failed standard treatments.
Engineered immune cells target CD19+ cancer cells in patients with treatment-resistant lymphoma and leukemia.
Innovative immunotherapy approach converts patient tumor cells into personalized vaccines to fight aggressive brain cancer.
Researchers modified children's own immune cells to fight B-cell leukemia and lymphoma when standard treatments failed.
Modified immune cells targeting GD2 protein demonstrated safety in treating aggressive childhood cancers like neuroblastoma and osteosarcoma.
Small trial tests innovative treatment IBI346 for blood cancer patients who didn't respond to standard therapies.
Phase II trial tested nivolumab with or without ipilimumab in 164 patients with metastatic sarcoma that couldn't be surgically removed.
A phase I/II trial tests SV-BR-1-GM, a whole-cell cancer vaccine, combined with the checkpoint inhibitor retifanlimab in patients with metastatic breast cancer.
Small trial tests novel three-drug approach combining immune checkpoint inhibitor, vaccine, and inflammation blocker for metastatic cancers.
Phase 1 trial of acapatamab, a PSMA-targeting bispecific T-cell engager, enrolls 212 men with metastatic castration-resistant prostate cancer.
A completed phase I trial tests regorafenib plus dual checkpoint inhibitors in 39 patients with hard-to-treat metastatic colorectal cancer.
MD Anderson's Phase 1/2 trial explored injecting rituximab directly into spinal fluid to target CNS lymphoid malignancies.
A first-in-human Phase 1/2 trial of ISB 1442 in relapsed/refractory multiple myeloma was halted before completion.