MSC Therapy Shows Promise Despite Mixed Clinical Results
Review reveals safety of mesenchymal stem cell therapy but highlights efficacy challenges in clinical trials.
20 articles
Review reveals safety of mesenchymal stem cell therapy but highlights efficacy challenges in clinical trials.
Comprehensive review reveals how MSCs repair tissues and modulate immunity across multiple diseases, offering new therapeutic pathways.
A comprehensive 2025 review reveals how MSCs repair damaged livers through immunomodulation, anti-fibrotic action, and regenerative signaling.
New review consolidates MSC biology breakthroughs, clinical approvals, and the standardization hurdles still blocking broader therapeutic success.
A 2025 review maps preclinical and clinical evidence for MSC therapy in Alzheimer's, detailing mechanisms, limitations, and future directions.
A comprehensive 2025 review maps the mechanisms, sources, and clinical applications of mesenchymal stem cells and their derived exosomes across cardiovascular, neurological, autoimmune, and musculoskeletal diseases.
Phase Ia/Ib dose-escalation trials reveal MSC therapy is safe in decompensated liver cirrhosis, with higher doses producing stronger immune rebalancing effects.
Combining mesenchymal stem cell transplantation with exercise may overcome key limitations of standalone therapy for sarcopenia.
Scientists created modified stem cells that home to bone marrow, delivering targeted immune therapies while avoiding tumors entirely.
Tiny particles from stem cells could deliver therapeutic benefits without the risks of traditional cell-based treatments.
Combining nanoparticles with mesenchymal stem cells could finally overcome the poor survival and differentiation that limits cartilage regeneration.
Scientists explore safer alternatives to stem cell transplants using cellular secretions that may offer similar benefits.
A comprehensive review maps how mesenchymal stem cells and their exosomes combat Alzheimer's, atherosclerosis, osteoporosis, and ovarian failure.
Analysis of 449 clinical trials reveals mesenchymal stem cells are leading treatment for osteoarthritis and rheumatoid arthritis worldwide.
Transplanted young muscle stem cells improved motor function and reduced anxiety in aged mice through enhanced blood vessel growth.
Human umbilical cord stem cells and their exosomes combat dexamethasone-induced muscle wasting via estrogen receptor pathways in mice and cell models.
A phase 2b trial finds allogeneic MSC infusions improved 6-minute walk distance by 63 meters vs placebo at 9 months in frail older adults.
New research reveals how tiny cellular packages from stem cells could revolutionize treatment for this devastating muscle disease.
Dual stem cell therapy from fat tissue dramatically reduces limb amputation risk by rebuilding blood vessels in severe circulation disease.
Engineered vesicles deliver healthy mitochondria to damaged brain vessels post-stroke, reprogramming metabolism and triggering angiogenesis in mice.