Stem Cell-Derived Hepatocytes Could Replace Liver Transplants
A translational review outlines how stem cell technologies may finally make hepatocyte-based liver therapies clinically viable.
20 articles
A translational review outlines how stem cell technologies may finally make hepatocyte-based liver therapies clinically viable.
A major review in Nature Medicine explores how CAR cell therapies may achieve deep immune 'reset' in autoimmune diseases by depleting pathogenic B cells.
New review explores how 3D organoids and bioengineered niches are revolutionizing tumor research and treatment development.
A new Cell Metabolism review from NIH identifies how ECM stiffening, poor blood flow, and mitochondrial failure lock tissues into accelerating decline.
A new review reveals how epithelial-to-mesenchymal transition fuels tumor invasion, immune evasion, and drug resistance through dynamic, reversible states.
New review reveals how senescent cells both prevent and promote cancer, opening therapeutic opportunities.
A new review reframes how myeloid cells fuel or fight tumors, pointing to plasticity โ not just cell diversity โ as the core therapeutic target.
New review reveals how advanced genomics tools are revolutionizing cancer diagnosis and therapy development.
A landmark review maps the three pillars of modern lineage tracing and how they're reshaping our understanding of cell fate decisions.
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
A Cochrane review of 4 RCTs finds no reliable evidence that adding endovascular stenting to medical therapy prevents stroke or death in vertebral artery stenosis.
A Dana-Farber review maps the path for personalized cancer vaccines โ pinpointing which tumors, timing, and combination strategies will matter most.
A new review reframes magnesium as a master regulator of mitochondrial energy, metabolic disease, and biological aging.
A landmark review reveals how diet, gut bacteria, and their metabolites determine the success of immune checkpoint blockade cancer therapy.
New research reveals how tumors might hijack sympathetic nervous system signals to boost their metabolism and proliferation.
New computational advances help identify which tumor peptides trigger immune responses, potentially revolutionizing personalized cancer therapy.
Researchers outline innovative approaches to speed up drug development for age-related diseases and longevity interventions.
A new review maps the bidirectional crosstalk between gut microbiota and cellular senescence driving multi-organ degeneration.
A new perspective in Nature Cancer outlines how genetically engineered bacteria can target and destroy tumors from within.
The British Society of Gastroenterology's expert panel takes stock of 10 years of microbiome advances and where the field is headed.