Metformin's Anti-Aging Promise Faces Growing Scientific Scrutiny
A major review challenges the evidence behind metformin as a longevity drug, exposing methodological flaws in landmark studies.
6 articles
A major review challenges the evidence behind metformin as a longevity drug, exposing methodological flaws in landmark studies.
Master the advanced molecular architecture of AMPK โ from isoform-specific signaling and spatial compartmentalization to emerging pharmacological strategies targeting the energy sensor at the heart of longevity biology.
A deep mechanistic exploration of mTOR complex architecture, allosteric regulation, and the cutting-edge therapeutic strategies targeting this pathway for healthspan extension.
Dr. Nir Barzilai presents his landmark centenarian studies and the FAST aging initiative, outlining the future of geromedicine.
Dr. Nir Barzilai outlines existing FDA-approved drugs with geromedicine potential and shares insights from decades of centenarian research.
New research reveals metformin's complex effects on aging - protecting frail adults while potentially limiting muscle gains in active individuals.