Diabetes Drug Metformin Shows Promise for HIV Suppression and Immune Control
New research reveals metformin can silence HIV and boost immune control, offering hope for treatment-free remission.
20 articles
New research reveals metformin can silence HIV and boost immune control, offering hope for treatment-free remission.
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
New research reveals how a single antibody treatment creates lasting protection against autoimmune diabetes by reshaping immune cells.
Senescent cells drive cyst growth in ADPKD, and targeting them with senolytics or the aldose reductase inhibitor epalrestat delays disease progression.
New research reveals why giving multiple doses of a promising type 1 diabetes treatment doesn't improve outcomes beyond a single course.
Comprehensive review reveals autoimmune markers present before symptoms and highlights automated insulin delivery breakthroughs.
Stanford researchers used modified immune proteins to enhance neurogenesis and cognitive function in aged mouse brains.
Go beyond inflammaging basics to understand how aging reshapes immune cell populations, triggers the SASP, and locks the body into a state of chronic low-grade inflammation at the molecular level.
Natural flavonoid fisetin activates mitophagy and xenophagy pathways to restrict intracellular Salmonella growth in immune cells.
Targeting immune diseases before symptoms appear can delay clinical onset by over two years, offering new prevention strategies.
BNT162b2 mRNA vaccine induces special immune cells that protect against severe illness and may slow aging-related decline.
Master the molecular architecture of complement dysregulation in aging — from regulatory protein biochemistry to cutting-edge therapeutic targets — and understand how precision interventions can restore balance without dismantling immunity.
A murine arthritis study finds rapamycin suppresses neuropeptide Y, linking cellular senescence to joint inflammation via SASP cytokines.
Discover how persistent low-grade inflammation drives the aging process and learn strategies to combat this silent threat to longevity.
New research reveals how IL-2 signaling generates special B cells that produce anti-inflammatory compounds, potentially slowing aging processes.
Scientists reveal how macrophages use mitochondria to clear dead cells while controlling immune responses, offering insights for healthier aging.
GZMK+CD8+ T cells promote chronic inflammation and aging-related disease—a newly recognized immune threat beyond cytotoxicity.
New research reveals how albumin, a common blood protein, may protect against life-threatening fungal infections.
A multi-biomarker study finds pwMS show accelerated thymic involution, senescent T cell expansion, and neuroinflammation linked to aging.
Pyruvate, a core metabolic molecule, suppresses interferon signaling by directly modifying STAT1 — linking metabolism to immune control.