20 articles
Large study finds diabetes drug metformin only slightly slows harmful blood cell mutations, questioning its use for cancer prevention.
Large UK study reveals metformin users have dramatically lower rates of dangerous DNMT3A mutations that lead to blood cancer.
New research reveals popular weight-loss medications may reduce cancer risk beyond their metabolic benefits.
Cambridge scientists engineer a nanoprobe that detects therapy-induced senescence non-invasively through a simple urine colorimetric test.
Metabolite supplement protects heart from chemo toxicity and enhances tumor suppression in breakthrough dual-action study.
A growth factor called GDF11 reprograms pro-tumor macrophages by rewiring their metabolism, suppressing hepatocellular carcinoma growth.
Redirecting glucose metabolism during T cell expansion dramatically improves cancer immunotherapy effectiveness.
New research reveals how popular weight-loss medications could offer unexpected cancer protection benefits.
A 10-week supervised strength program targets chronic inflammation and self-efficacy in long-term allogeneic HCT survivors.
Scientists found drugs that kill senescent 'zombie cells' by blocking their key survival protein, shrinking tumors in mice.
A study of 110,000+ women found GLP-1 users had ~30% lower breast cancer risk, sparking plans for clinical trials.
New research reveals how ฮฑ-ketoglutarate regulates AMPK synthesis, offering potential cancer therapy targets through energy stress.
Inqovi gains approval for newly diagnosed AML in patients 75+ or with comorbidities, offering a gentler oral treatment route.
ASTER 70s trial compares treatment intensities for women 70+ with genomically high-risk breast cancer to optimize outcomes while minimizing toxicity.
Study identifies senescent EGR1+ B cells that sabotage immunotherapy in esophageal cancer, with fisetin showing promise as a therapeutic enhancer.
New review reveals how senescent cells both prevent and promote cancer, opening therapeutic opportunities.
Scientists develop advanced drug delivery methods to detect and eliminate harmful senescent tumor cells that promote cancer spread.
New research reveals senescent cells have both harmful and protective roles, pushing anti-aging science toward targeted removal strategies.
A mouse study finds that senolytic drugs cannot prevent chemotherapy-driven bone loss, challenging a leading hypothesis about its cause.
Engineered green tea compound nanoparticles activate cellular powerhouses to suppress tumor growth and improve immune response against melanoma.
