Cancer Research
Metformin Blocks Cancer-Causing Blood Cell Mutations in 400K+ People
Large UK study reveals metformin users have dramatically lower rates of dangerous DNMT3A mutations that lead to blood cancer.
Research Paper
Apr 13, 2026 0
Results for "Metformin TAME Trial" in Cancer
20 articles
Cancer Research
Metformin Shows Minimal Effect on Blood Cell Mutations Linked to Cancer Risk
Large study finds diabetes drug metformin only slightly slows harmful blood cell mutations, questioning its use for cancer prevention.
Research Paper
Mar 29, 2026 1
Cancer Research
New c-Met Antibody-Drug Conjugate Shows Promise in Late-Stage Colorectal Cancer
Phase I trial of Temab-A reports 15.6% response rate and 74.6% disease control in heavily pretreated metastatic colorectal cancer patients.
Research Paper
May 3, 2026 0
Cancer Research
Belantamab Mafodotin Combos Show Promise in Relapsed Multiple Myeloma Trial
GSK's Phase 1/2 trial tests belantamab mafodotin paired with standard regimens in patients who failed prior myeloma therapy.
Clinical Trial
Jun 9, 2026 0
Cancer Research
Talquetamab Shows 60% Response Rate in Japanese Myeloma Patients with No Dose-Limiting Toxicity
Phase 1 data from 15 heavily pretreated Japanese myeloma patients confirms talquetamab's safety and efficacy, matching global trial results.
Research Paper
Jun 15, 2026 0
Cancer Research
HDAC Inhibitor Plus Checkpoint Blocker Tested in Advanced Lung Cancer Trial
A phase 1/2 trial combined mocetinostat and durvalumab in 83 patients with advanced solid tumors and NSCLC.
Clinical Trial
May 7, 2026 0
Cancer Research
Targeted Therapy Shows Promise for Aggressive Brain Cancer in Precision Medicine Trial
Phase 1/2 umbrella trial matches glioblastoma patients to targeted treatments based on tumor genetics, with temsirolimus showing significant benefit.
Research Paper
Apr 4, 2026 0
Cancer Research
Tumor-Targeted CD40 Antibody Shows Safe Profile but Limited Tumor Shrinkage in Phase 1 Trial
RO7300490, a FAP-targeted CD40 agonist, proved manageable in 80 advanced cancer patients but produced no objective tumor responses despite clear immune activation.
Research Paper
May 2, 2026 0
Cancer Research
Phase I Trial Tests Triple Drug Combo for BRAF-Mutant Metastatic Solid Tumors
MD Anderson researchers evaluated vemurafenib, cetuximab, and irinotecan together to find the optimal dose and safety profile for advanced solid tumors.
Clinical Trial
Jun 5, 2026 0
Cancer Research
GLP-1 Drugs Like Ozempic Linked to 30% Lower Breast Cancer Risk in Major Study
A study of 110,000+ women found GLP-1 users had ~30% lower breast cancer risk, sparking plans for clinical trials.
Press Release
Jun 7, 2026 0
Cancer Research
Novel Tumor-Targeted CD40 Drug Safely Reprograms Cancer Immune Environment
Phase 1 trial shows MP0317 activates anti-tumor immunity in solid tumors with a favorable safety profile, supporting combination therapy.
Research Paper
May 2, 2026 0
Cancer Research
Dual Checkpoint Blockade Plus FOLFOX Chemo Tested in Metastatic Colorectal Cancer
A Phase 1/2 trial tests whether combining durvalumab, tremelimumab, and FOLFOX chemotherapy can safely boost immune response in mCRC.
Clinical Trial
May 17, 2026 0
Cancer Research
GLP-1 Drugs Like Ozempic Show Unexpected Cancer Protection Benefits
New research reveals popular weight-loss medications may reduce cancer risk beyond their metabolic benefits.
Research Paper
Mar 29, 2026 1
Cancer Research
Immunotherapy Plus T-DXd Shows Strong Results in HER2-Low Breast Cancer
The BEGONIA trial finds durvalumab combined with trastuzumab deruxtecan achieves 62% response rate in hard-to-treat metastatic breast cancer.
Research Paper
Jun 9, 2026 0
Cancer Research
Vitamin D Receptor Agonist Reshapes Pancreatic Cancer's Defensive Shield
A phase trial finds paricalcitol safely remodels the tumor microenvironment in metastatic pancreatic cancer, boosting immune cell infiltration.
Research Paper
May 26, 2026 0
Cancer Research
Radiation to Metastases Cuts Cancer Progression Risk in Half in Phase II Trial
Adding targeted radiation to standard therapy reduced progression by 46% across multiple cancer types in the EXTEND trial.
Research Paper
May 19, 2026 0
Cancer Research
New Cancer Immunotherapy IBI346 Shows Promise in Multiple Myeloma Trial
Small trial tests innovative treatment IBI346 for blood cancer patients who didn't respond to standard therapies.
Clinical Trial
Mar 28, 2026 1
Cancer Research
New Triple Drug Combo Doubles Survival for Brain Metastases in HER2+ Breast Cancer
Tucatinib-based treatment extends survival from 4.4 to 10 months for women with breast cancer that spread to brain lining.
Research Paper
Mar 28, 2026 0
Cancer Research
Chemotherapy Plus Hormones vs Hormones Alone for Older Women with High-Risk Breast Cancer
ASTER 70s trial compares treatment intensities for women 70+ with genomically high-risk breast cancer to optimize outcomes while minimizing toxicity.
Research Paper
Apr 4, 2026 0
Cancer Research
DCA Metabolic Conditioning Creates Superior Cancer-Fighting T Cells
Redirecting glucose metabolism during T cell expansion dramatically improves cancer immunotherapy effectiveness.
Research Paper
Mar 29, 2026 0
Page 1 of 2Next