20 articles
Demethyleneberberine, derived from traditional Chinese medicine, significantly reduced lung scarring by targeting NLRP3 inflammasome and EMT in mice.
Researchers tested whether eosinophil β1 integrin activation in blood could track disease activity, potentially sparing patients repeat invasive procedures.
Latest advances in molecular diagnostics may revolutionize how clinicians detect and manage antibiotic-resistant gonorrhea infections.
A randomized phase 2 trial finds CM313 achieves 83% response rate vs 20% placebo in treatment-resistant immune thrombocytopenia.
Structural biology uncovers the exact amino acid motif causing species-specific drug failures, enabling transgenic mouse models for better P2X7 drug testing.
Natural flavonoid fisetin activates mitophagy and xenophagy pathways to restrict intracellular Salmonella growth in immune cells.
A new veterinary sedative is contaminating the illegal fentanyl supply, posing novel overdose risks that standard treatments may not reverse.
Advanced lung biopsy technique uncovers serious pneumonia complications from methotrexate treatment in rheumatoid arthritis patients.
A phase 1/2 trial finds low-dose oral NMN safely raises platelet counts in steroid-refractory ITP via a novel immunometabolic mechanism.
Scientists mapped key attack sites on measles virus proteins, finding human antibodies that powerfully neutralize MeV before and after exposure.
International study reveals concerning inconsistencies in myositis antibody testing that could affect diagnosis and treatment decisions.
New research reveals how immune cells use cysteine for both antioxidant defense and energy production, with major implications for cancer treatment.
New research reveals efgartigimod reshapes B-cell populations in myasthenia gravis, inducing regulatory plasma cells linked to clinical improvement.
A 2025 review from Johns Hopkins outlines how to accurately diagnose complement-mediated TMA using functional assays and systematic testing.
New study reveals specific immune and microbiome signatures that could predict depression in lupus patients with 85% accuracy.
New research reveals E. coli dominates and suppresses S. aureus in dual-species implant biofilms, with major implications for treating polymicrobial joint infections.
A Stanford RCT finds pulsed electromagnetic field therapy significantly reduces thumb CMC osteoarthritis pain at 6 weeks, even after treatment ends.
Scientists discover unique immune peptide patterns in Behçet's disease patients that trigger harmful inflammation responses.
New research reveals how metabolic molecules function as signaling agents that control immune responses within tumors.
A completed trial tests whether diode laser treatment reduces TLR-4 in saliva, linking periodontal inflammation to systemic aging biology.
