Liquid Biopsy Guides Targeted Lung Cancer Treatment in Breakthrough Trial
New study shows how analyzing fluid from lungs can detect cancer mutations and guide personalized treatment decisions.
20 articles
New study shows how analyzing fluid from lungs can detect cancer mutations and guide personalized treatment decisions.
New liquid biopsy technique identifies molecular residual disease in colorectal cancer patients to guide personalized treatment decisions.
Small trial tests innovative treatment IBI346 for blood cancer patients who didn't respond to standard therapies.
Small study explores cerebrospinal fluid exosomes to better diagnose breast cancer spread to brain and spinal cord.
GSK's Phase 1/2 trial tests belantamab mafodotin paired with standard regimens in patients who failed prior myeloma therapy.
A completed phase 3 trial compared A+AVD versus ABVD for advanced classical Hodgkin lymphoma, testing whether replacing bleomycin with brentuximab vedotin improves outcomes.
A Phase II NCI trial testing bintrafusp alfa in metastatic urothelial carcinoma was terminated after enrolling only 2 patients.
A first-in-human Phase 1/2 trial of ISB 1442 in relapsed/refractory multiple myeloma was halted before completion.
MD Anderson's Phase 1/2 trial explored injecting rituximab directly into spinal fluid to target CNS lymphoid malignancies.
A phase 1/2 trial combined mocetinostat and durvalumab in 83 patients with advanced solid tumors and NSCLC.
A Phase 1/2 trial tests whether combining durvalumab, tremelimumab, and FOLFOX chemotherapy can safely boost immune response in mCRC.
A Phase 2 trial explores whether oral curcumin can enhance Avastin/FOLFIRI chemotherapy outcomes in patients with unresectable colorectal metastases.
Genetically modified immune cells target blood cancer that stopped responding to standard treatments in 28-patient trial.
A completed NCI trial evaluated advanced imaging and breast duct lavage in women with BRCA1/BRCA2 mutations to improve early cancer detection.
Phase 1 trial evaluates PF-06863135 (elranatamab) alone and with immunomodulatory agents to find safe dosing in heavily pretreated myeloma patients.
New diagnostic chip analyzes blood exosomes to detect early lung spread of bone cancer, potentially improving treatment outcomes.
French researchers studied how tiny cellular packages called exosomes may help melanoma cells resist treatment and spread throughout the body.
MD Anderson researchers evaluated vemurafenib, cetuximab, and irinotecan together to find the optimal dose and safety profile for advanced solid tumors.
Scientists modified patients' immune cells to better recognize and attack cancer tumors expressing NY-ESO-1 protein.
A completed exploratory trial evaluates whether a specialized compression garment can reduce discomfort and improve quality of life in pelvic lymphedema patients.