20 articles
New research reveals that mitochondrial energy pathways directly govern dendritic cell immune activation, with major implications for cancer and autoimmune therapies.
Scientists reveal how macrophages use mitochondria to clear dead cells while controlling immune responses, offering insights for healthier aging.
New research reveals how a mitochondrial enzyme enhances immune cell function to fight bacterial lung infections and reduce inflammation.
Mitochondrial complex II in intestinal cells regulates T cell immune responses and inflammation pathways.
Scientists discover how immune cells work together in unexpected ways, opening new paths for cancer therapy and transplant success.
New research reveals how necroptosis activates immune pathways, offering targets for inflammatory bowel disease treatment.
Researchers uncover how the STING immune pathway triggers mitochondrial fragmentation and DNA release, fueling deadly lung inflammation in sepsis.
New research reveals how circulating factors in autoimmune disease blood can directly cause muscle weakness and cellular dysfunction.
Phase 1 trial examines whether vesatolimod can safely stimulate immune response in HIV controllers during treatment interruption.
Revolutionary cell therapy achieves drug-free remission in patients with severe myasthenia gravis, an autoimmune muscle disorder.
New research identifies Lp-PLA2 enzyme as therapeutic target for deadly lung disease affecting millions of workers worldwide.
RA patients with interstitial lung disease show accelerated cellular aging markers โ shorter telomeres and fewer mitochondrial DNA copies than RA patients without lung involvement.
Pyruvate, a core metabolic molecule, suppresses interferon signaling by directly modifying STAT1 โ linking metabolism to immune control.
A phase 1/2 trial finds low-dose oral NMN safely raises platelet counts in steroid-refractory ITP via a novel immunometabolic mechanism.
Researchers modified NK and T cells with special receptors that help them track down and infiltrate solid tumors more effectively.
A major review outlines how targeted hematologic therapies are transforming outcomes in MGRS, a rare but serious cause of kidney injury.
A completed Phase 3 trial tests placental MSC secretome injections against placebo in 60 GvHD patients at an Iranian hospital.
Structural biology uncovers the exact amino acid motif causing species-specific drug failures, enabling transgenic mouse models for better P2X7 drug testing.
A new in vitro study shows Thymosin ฮฑ1 triggers dendritic cells to release IL-15, boosting CD8+ T cell killing and reducing HIV reservoir size.
New research reveals how immune cells use cysteine for both antioxidant defense and energy production, with major implications for cancer treatment.
